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Study aims to speed up osteoporosis diagnosis

Press release: 11 July 2011

A University of Manchester scientist has won funding from a leading medical research charity to develop a more effective way of routinely detecting osteoporosis in the spine.

Tim Cootes, Professor of Computer Vision in the School of Cancer and Enabling Sciences, has been awarded £136,600 over two years from Arthritis Research UK.

Working with Professor Judith Adams at Manchester Royal Infirmary, Professor Cootes and his team aim to produce a new computer program to detect fractured vertebrae in radiographs, which are commonly used to diagnose osteoporosis. Currently, up to 50% of fractured vertebrae are missed, as identifying them requires considerable expertise.

"The tool will automatically measure the shape of each vertebra and indicate if they are damaged or unusual, so helping clinicians to detect vertebral fractures more reliably and quickly," said Professor Cootes. "This will help to diagnose osteoporosis at an earlier stage, leading to earlier treatment and reducing the risk of future fractures."

Osteoporosis is a condition affecting the bones, causing them to weaken and fracture. Around 3 million people in the UK have the disease, mainly post-menopausal women, leading to more than 230,000 fractures as a result. However, lifestyle changes and drug treatments can significantly reduce the risk of fractures so early diagnosis is important.

An early sign of the disease is fracture of the vertebrae, but because they often cause no discomfort they can go unnoticed by the patient.

"We've developed a computer system that can distinguish between normal and fractured vertebrae, and in this project we aim to improve the system further and to train it to work on the different types of x-ray images that are commonly used," added Professor Cootes.

"We'll examine routine clinical images to test if the tool is reliable enough to help clinicians in normal examinations."

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Aeron Haworth
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The University of Manchester

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Email: aeron.haworth@manchester.ac.uk

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