Brain injury research
The Brain Injury Research Group is based at Salford Royal NHS Foundation Trust and includes both clinical and non-clinical research scientists investigating brain damage due to vascular dysfunction and trauma.
Research is multidisciplinary, encompassing laboratory studies, human physiology, neuro-critical care and imaging, genetics, rehabilitation and clinical trials, with translation of basic science into clinical practice as a major aim. This involves major collaboration with the:
- Faculty of Life Sciences: Neurosciences Group
- Faculty of Medicine and Human Sciences: Imaging Sciences Research Group
- Salford Royal: Departments of Neurosurgery and Intensive Care Medicine
Research programmes focus on clinical studies to investigate the aetiology, mechanisms and treatment of, and recovery from, neurological injury.
Research projects
Curent research projects include:
- Pharmacokinetics and efficacy of Interleukin-1 receptor antagonist in sub-arachnoid haemorhage and stroke
- TIA and inflammation
- Sub-arachnoid haemorrhage and inflammation
- Brain temperature and outcome after severe head injury
- S-100B as a prognostic indicator for outcome after brain injury
Research is funded by the Jules Thorn Charitable Trust, Medical Research Council (MRC), National Institute for Health Research (NIHR), Wellcome Trust and other charities. Many stroke studies are also supported by the North West Stroke Research Network, which operates from Salford Royal NHS Foundation Trust.
We seek the involvement of patients and the public in the development of our research programmes.
Recent events
'Raised Human Brain Temperature - Good or Bad After Traumatic Brain Injury?'
Date: 26 November 2008
Venue: Chancellors Hotel and Conference Centre, Manchester, UK
Symposium and workshop programme (PDF, 240 KB)
'Brain Inflammation Research Group: understanding what we can do best'
Date: 2 February 2009
Venue: Chancellors Hotel and Conference Centre, Manchester, UK
Conference and workshop programme (PDF, 28 KB)
Principal research group members
| Name | Job title | Email address |
|---|---|---|
| Dr Charmaine Childs | Senior Research Fellow (Hon Senior Lecturer) | charmaine.childs@manchester.ac.uk |
| James Galea | Research SpR, Neurosurgery | james.galea@manchester.ac.uk |
| Margaret Hoadley | Senior Research Scientific Officer (Hon Faculty Fellow) | margaret.hoadley@manchester.ac.uk |
| Dr Steve Hopkins | Consultant Healthcare Scientist (Hon Reader) | Steve.Hopkins@manchester.ac.uk |
| Sharon Hulme | Research Nurse | sharon.hulme@manchester.ac.uk |
| Karen Illingworth | Technician | karen.illingworth@manchester.ac.uk |
| Dr Andrew King | Consultant Neurosurgeon | andrew.king@srft.nhs.uk |
| Adrian Parry-Jones | Research Fellow, Stroke Rehabilitation | adrian.parry-jones@srft.nhs.uk |
| Dr Maxine Power | Associate Director of Quality Improvement | maxine.power@srft.nhs.uk |
| Timothy Rainey | Technician | timothy.rainey@manchester.ac.uk |
| Raphael Sacho | Research SpR, Neurosurgery | raphael.sacho@postgrad.manchester.ac.uk |
| Sylvia Scarth | Technician | sylvia.scarth@manchester.ac.uk |
| Dr Craig Smith | Consultant in Stroke Medicine/Honorary Lecturer | craig.smith-2@manchester.ac.uk |
| Dr Pippa Tyrrell | Senior Lecturer (Hon. Consultant Stroke Medicine) | pippa.tyrrell@manchester.ac.uk |
Collaborators: Manchester
| Name | Job title | Email address |
|---|---|---|
| Alistair Burns | Professor of Old Age Psychiatry | alistair.burns@manchester.ac.uk |
| Charles McCollum | Professor of Surgery | charles.mccollum@manchester.ac.uk |
| Nancy Rothwell | MRC Research Professor | nancy.rothwell@manchester.ac.uk |
Collaborators: outside Manchester
| Name | Job title | Email address |
|---|---|---|
| Alastair Buchan | Director, NIHR, Biomedical Research | University of Oxford |
| Keri Carpenter | University of Cambridge | |
| Samantha Grainger | Research Nurse, Neurosurgery | sam505@tiscali.co.uk |
| Peter Hutchinson | Senior Academic Fellow and Hon Consultant Neurosurgeon | University of Cambridge |
| Keith Muir | Senior Lecturer, Clinical Neurosciences Centre | University of Glasgow |
| Elizabeth Warburton | University of Cambridge |
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