Clinical Neurosciences Research within the School of Translational Medicine
Clinical Neurosciences

Neuro-oncology

Neuro-oncological research is a highly interdisciplinary endeavour that is based on the comprehensive neuro-oncological service provided by clinicians at Salford Royal NHS Foundation Trust in cooperation with Christie Hospital NHS Foundation Trust, which includes a weekly multidisciplinary brain tumour board.

Current research focuses on development of imaging biomarkers for grading of tumour malignancy and monitoring of tumour progression. This employs new technological developments for magnetic resonance imaging (MRI) at the Translational Imaging Unit (TIU) and positron emission tomography (PET) at the Wolfson Molecular Imaging Centre (WMIC).

In-vivo imaging biomarkers are studied in correlation with ex-vivo molecular and histochemical techniques. Preclinical studies are performed in collaboration with the Paterson Institute for Cancer Research.

Principal investigators

Name Job title Email adress
Professor Karl Herholz Director of WMIC / Professor of Clinical Neuroscience karl.herholz@manchester.ac.uk
Professor Alan Jackson  Professor of Radiology
 
alan.jackson@manchester.ac.uk
Dr Daniel Du Plessis Honorary Lecturer / Consultant Neuropathologist Daniel.Duplessis@srft.nhs.uk
Improving diagnosis in brain tumours
Combining advanced imaging techniques (Fused MRI with PET 'RatioMap' image highlighting tumour
in red)