Past research project examples

Enrique Amaya, Ardeshir Bayat

Characterisation of immune cells in the frog skin

Ardeshir Bayat

Detection of biomarkers in breast capsular contracture

Anne-Marie Buckle

Creation of three dimensional stem cell niches

Sandra Downes and Paul Bishop

A novel polymer for retinal pigment epithelial cells

Julie Gough

Resorbable magnesium alloys for bone repair

Denis Headon and Sarah Herrick

Hair follicle regeneration in wound repair

Judith Hoyland and Stephen M. Richardson

Immunohistochemical analysis of type VI collagen in the pericellular matrix of native and engineered stem cell-based tissues

Judith Hoyland and Stephen M. Richardson

Immunohistochemical analysis of proteoglycans in native and engineered stem cell- based tissues

Judith Hoyland and Dr Christine Le Maitre

Impact of in vitro Expansion on the differentiation potential of intervertebral disc cells:
Implications For Tissue Regeneration Strategies

Judith Hoyland and Christine Le Maitre

The interaction between notochordal cells and intervertebral disc cells: implications for novel tissue engineering/regenerative strategies for the intervertebral disc

Judith Hoyland and Stephen M. Richardson

Improved chondrocyte differentiation of human mesenchymal stem cells in a hydrogel system by addition of exogenous growth factors: a potential tissue engineering approach for the degenerate intervertebral disc

Karl Kadler

Multipotency of stem cells in tendon and ligament injury

Sue Kimber

Targeting differentiation of human ES cells to endoderm

Ian Kinloch and Sandra Downes

The effect of a growth substrate's topology on the nanoscale on cell behaviour

Georges Lacaud & Valerie Kouskoff

Tracking of Haematopoietic Cells Generated from Embryonic Stem Cells

Kia Langford, Brian Bigger

Analysis of tolerance to human Factor IX following stem cell transplantation in a haemophiliac mouse model

Vivek Madura, Gus McGrourther, Ardeshir Bayat

Identification of genes involved in matrix remodeling in skin fibroblasts under tensional load

Cathy Merry and Julie Gough

Investigating stem cells at the ultrastructural level

Angharad O’Leary, Brian Bigger

Analysis of stem cell homing towards bone marrow stromal layers in MPS disease

Angharad O’Leary, Brian Bigger

Examining CD26 inhibition as a mechanism for improving stem cell engraftment efficiency

Giorgio Terenghi and Paul Kingham

Regenerative mechanisms of injured laryngeal muscles

Giorgio Terenghi and Sandra Downes

Schwann cells and stem cell proliferation and differentiation on extracellular matrix molecule modified substrate

Caroline M Milner, Ardeshir Bayat

The role of hyaluronan in skin scar formation

Jane Millward-Sadler

Effect of integrins on matrix regulation in osteoarthritic chondrocytes

Jane Millward-Sadler

Mechanical regulation of matrix production in human bone cells

Jane Millward-Sadler, Judith Hoyland

Expression of ATP receptors in normal and degenerate intervertebral disc

Nicola Tirelli and Chirag Gujral

Preparation of functional derivatives of hyaluronic acid

Nicola Tirelli, Chirag Gujral, Manuela DiBiase

Use of hyaluronic acid derivatives of for ink-jet printing of biofunctional hydrogels

Nicola Tirelli, Suwipa Ungphaiboon

Preparation of matrix components that exhibit a controlled binding to sulphated glycosoaminoglycanes

Nicola Tirelli, Suwipa Ungphaiboon, Sihem Ouasti

Characterisation of the cellular uptake of fluorescently labelled polysaccharides

Rein V Ulijn and Cathy Merry

Bioactive Peptide/Saccharide Scaffolds for 3D Culture of Stem Cells

Rein V Ulijn and Julie Gough

Exploiting Enzyme Assisted Self-Assembly in 3D Cell Culture (EASy Gel)

Fiona Wilkinson

Developing a lentiviral gene delivery system in stem cell subsets for the treatment of mucopolysaccharide disease (MPS).