Dr Rebecca Elliott , BA, PhD

Senior Research Fellow in Cognitive Neuroscience
- Email: rebecca.elliott@manchester.ac.uk
- Telephone: +44 (0)161 275 7433
Research
My research interests focus on understanding the neurobiological basis of emotional, motivational and social processes, particularly in the context of psychiatric disorders.
I use a combination of brain imaging techniques (particularly functional magnetic resonance imaging, fMRI) and neuropsychological testing to explore neurocognitive aspects of emotional, motivational and social function, in healthy volunteers and patients with neuropsychiatric problems. With my colleagues in the Neuroscience and Psychiatry Unit, I also study how these functions are modulated by pharmacological interventions.
My main current projects are: (i) exploring the effects of treatment on emotional functions in depression; (ii) exploring the neurobiological basis of resilience to depression in the face of acute and chronic stress; (iii) exploring interactions between physical health, depression and neurocognitive profile in older adults and (iv) exploring neurobiological mechanisms of craving and cognition in drug addiction and how these influence relapse.
I am also involved in methodological developments in cognitive brain imaging and neuropsychology., collaborating with colleagues in other research groups in Manchester and other universities in the UK and Europe to develop new paradigms for exploring emotional, motivational and social functions in a wide range of clinical populations.
I supervise a number of PhD students on projects relating to my research interests and am always happy to discuss potential research projects with students hoping to carry out PhD or postdoctoral research.
Recently I became involved in the STEMNET ambassador project, which aims to increase the involvement of professional scientists in public engagement activities, with an emphasis on school activities. Whether through STEMNET or other means, I welcome opportunities to discuss my research activities with a range of audiences.
Methodological Knowledge
Design, programming and interpretation of neuropsychological tests.
Design, programming and interpretation of cognitive challenge tasks to use with functional neuroimaging.
Teaching
MSc Psychiatry (School of Community Based Medicine)
MSc Cognitive Brain Imaging (School of Psychological Sciences)
Undergraduate teaching: supervisor for SSMs and project options for medical school undergraduates. I offer projects in the general area of psychiatry and brain function.
Collaborators and affiliated staff
Manchester collaborators:
- Elise Kleyn and Chris Griffiths, Dermatology. Neural basis of emotional dysfunction in chronic skin disease
- Anthony Jones, Rheumatology. Neural processing of pain.
- Ian Bruce, Rheumatology. Neural correlates of mood disturbance and fatigue in Lupus.
- Wael el-Deredy, School of Psychological Sciences. Reward processing mechanisms.
- Daniela Montaldi, School of Psychological Sciences. Emotional memory in depression.
- Penny Lewis, School of Psychological Sciences. Sleep and memory impairments in depression.
- Adrian Heald, Endocrinology. Neural mechanisms of antipsychotic-induced weight gain.
UK/European collaborators:
- Imperial College, University of Cambridge: new treatments for addiction.
- Anna Barnes, University of Cambridge: fractal analysis in fMRI
- Center for Integrated Molecular and Biological Imaging, Copenhagen: serotonin, impulsivity and depression.
- Asa Hammer, Kenneth Hugdahl, University of Bergen: neural mechanisms of executive functioning in depression.
Studentships available
Selected publications
2011
- Anderson IM, Juhasz G, Thomas E, Downey D, McKie S, Deakin JFW and Elliott R. (2011). The effect of acute citalopram on face emotion processing in remitted depression: a pharmacoMRI study. European Neuropsychopharmacology, 21(1), 140-148. eScholarID:84407 | DOI:10.1016/j.euroneuro.2010.06.008
2010
- Vollm BA, Richardson PC, McKie S, Reniers R, Elliott R, Anderson I, Williams SR, Dolan M, Deakin JFW. (2010). Neuronal correlates and serotonergic modulation of behavioural inhibition and reward in healthy and antisocial individuals. Journal of Psychiatric Research, 44, 123-131. eScholarID:1d21083 | DOI:10.1016/j.jpsychires.2009.07.005
2009
- Kleyn, CE, McKie, S, Ross, A, Montaldi, D, Gregory, LJ, Elliott, R, Isaacs, C, Anderson, I, Richards, HL, Deakin, JFW, Fortune, D, Griffiths, CEM. (2009). Diminished neural and cognitive responses to facial expressions of disgust in patients with psoriasis: a fMRI study. J Invest Dermatol, 129 (11), 2613-2619. eScholarID:1d21110 | DOI:10.1038/jid.2009.152
2008
- Anderson IM, McKie S, Elliott R, Williams SR, Deakin JFW. (2008). Assessing human 5-HT function in vivo with pharmacoMRI. Neuropsychopharmacology, 55(6), 1029-1037. eScholarID:1d21138
2007
- Anderson I, Del-Ben Cristina, McKie S, Richardson PC, Williams SR, Elliott R, Deakin JFW. (2007). Citalopram modulation of neuronal responses to face emotion: a functional MRI study. NeuroReport, 18(13), 1351-1355. eScholarID:1d21149
- Vollm BA, Richardson PC, McKie S, Elliott R, Dolan M, Deakin JFW. (2007). Neuronal correlates of reward and loss in Cluster B personality disorder: A functional magnetic resonance imaging study. Psychiatry Research: Neuroimaging, 15, eScholarID:1d14229
2004
- Elliott R, Alan Ogilvie, Judy S Rubinsztein, Gloria Calderon, Raymond J Dolan, Barbara J Sahakian. (2004). Abnormal ventral frontal response during performance of an affective go/nogo task in patients with mania. Biological Psychiatry, 55 (12), 1163-70. eScholarID:1d9065 | DOI:10.1016/j.biopsych.2004.03.007
- Elliott R, Jana L Newman, Olivia A Longe, Bill Deakin. (2004). Instrumental responding for rewards is associated with enhanced neuronal response in subcortical reward systems. Neuroimage, 21 (3), 984-90. eScholarID:1d9070 | DOI:10.1016/j.neuroimage.2003.10.010
2003
- Elliott R, Newman JL, Longe OA, Deakin JFW. (2003). Differential response patterns in the striatum and orbitofrontal cortex to financial reward in humans: a parametric fMRI study. Journal of Neuroscience, 23 (1), 303-307. eScholarID:1d5992
2002
- Elliott R, Rubinsztein J S, Dolan R J, Sahakian B J. (2002). The neural basis of mood congruent processing biases in depression. Arch Gen Psychiatry, 59 (7), 597-604. eScholarID:1d2696 | DOI:10.1001/archpsyc.59.7.597
Selected research projects
- ICCAM - New drugs for addiction: focus on attenuating core behavioural components of heroin, cocaine and alcohol addiction
- Neurobiology of cognition and craving in opiate addiction: implications for relapse
- Neurobiology of Resilience to Depression study
- The neural basis of response to treatment in depression: an fMRI and pharmacoMRI study (REMEDi study)