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School of Medicine

Mrs Ann Haylett 

Photograph of Ann Haylett

Honorary Lecturer

Photobiology Unit, Dermatological Sciences, Salford Royal Foundation Hospital, Manchester, M6 8HD

 

Role

As a Senior Healthcare Scientist I have several years’ research experience in the field of Photobiology. During my research career I have undertaken research in both in vivo and in vitro projects including investigating methods of improving and developing photodynamic therapy for the treatment of cancer. This work has included detailed examination of the effects of structural modifications of photosensitizers on sensitizer efficiency. Currently I am involved in a Wellcome Trust funded research collaboration between the Photobiology Unit and two external universities, and phototesting trials of an α-MSH analogue in the photoprotection of photosensitivity disorders. My publications include 11 original manuscripts and one book chapter. I have presented extensively at 5 international and 14 national conferences, including 2 invited talks. I have experience of both undergraduate and postgraduate teaching and supervision both at a tutorial level and at a project based level, including 2 PhDs. 

 

Publications

2009

  • Haylett AA, Rhodes LE. (2009). Evaluation of the patient with photosensitivity. Allergy Frontiers: Diagnosis and Health Economics. Springer. eScholarID:3d1084
  • Gledhill K, Brownrigg M, Haylett AA, Masoodi M, Thody AJ, Nicolaou A, Rhodes LE, Tobin DJ. (2009). Skin phototype does not correlate with melanogenic capability in epidermal melanocytes in vitro. eScholarID:2d2431
  • Gledhill K, Haylett AA, Brownrigg M, Masoodi M, Thody AJ, Nicolaou A, Rhodes LE, Tobin DJ. (2009). Leukocyte infiltration into human skin in response to UVR: Influence of skin photo-type?. eScholarID:2d2189
  • Haylett AA, Nie Z, Brownrigg M, Rhodes LE. (2009). Biomodulation of the solar urticarial response in human skin: targeting the melanogenic pathway with afamelanotide. eScholarID:2d2378
  • Haylett AA, Rhodes LE. (2009). Converting laboratory observations into clinical practice. eScholarID:2d2197

2008

  • Yesudian P, Berry JL, Wiles S, Hoyle S, Young D, Haylett AA, Rhodes LE, Davies P. (2008). The effect of ultraviolet B-induced vitamin D levels on host resistance to Mycobacterium tuberculosis: a pilot study in immigrant Asian adults living in the United Kingdom. Photodermatol Photoimmunol Photomed, 24( 2), 97-8. eScholarID:1d17548

2003

  • Haylett AA, Ward T, Moore J. (2003). DNA damage and repair in Gorlin syndrome and normal fibroblasts after aminolevulinic acid photodynamic therapy: a comet assay study. Photochem Photobiol, 78( 4), 337-41. eScholarID:1d18569

2002

  • Haylett AA, Higley K, Chiu M, Shackley D, Moore J. (2002). Collagen secretion after photodynamic therapy versus scar-inducing anti-cancer modalities: an in vitro study. Photochem Photobiol Sci, 1( 9), 673-7. eScholarID:1d18570
  • Haylett AA, Moore J. (2002). Comparative analysis of foetal calf and human low density lipoprotein: relevance for pharmacodynamics of photosensitizers. J Photochem Photobiol B, 66( 3), 171-8. eScholarID:1d18571
  • Shackley D, Haylett AA, Whitehurst C, Betts C, O'Flynn K, Clarke N, Moore J. (2002). Comparison of the cellular molecular stress responses after treatments used in bladder cancer. BJU Int, 90( 9), 924-32. eScholarID:1d12078

2001

  • Verrico A, Haylett AA, Moore J. (2001). In vivo expression of the collagen-related heat shock protein HSP47, following hyperthermia or photodynamic therapy. Lasers Med Sci, 16( 3), 192-8. eScholarID:1d18572

1998

  • Griffiths S, Heelis P, Haylett AA, Moore J. (1998). Photodynamic therapy of ovarian tumours and normal cells using 5,10,15,20-tetra-(3-carboxymethoxyphenyl)-chlorin. Cancer Lett, 125( 1-2), 177-84. eScholarID:1d18573

1997

  • Haylett AA, McNair F, McGarvey D, Dodd N, Forbes E, Truscott T, Moore J. (1997). Singlet oxygen and superoxide characteristics of a series of novel asymmetric photosensitizers. Cancer Lett, 112( 2), 233-8. eScholarID:1d18574

1996

  • Haylett AA, Forbes E, MacLennan A, Truscott T, Moore J. (1996). Novel asymmetric photosensitizers: an in vitro study. Cancer Lett, 105( 2), 187-93. eScholarID:1d18575

1995

  • Haylett AA, Ross S, Truscott T, Moore J. (1995). Pharmacokinetic and therapeutic outcome in melanoma cells, of the administration of symmetric and asymmetric cationic photosensitizers. Cancer Lett, 88( 2), 191-9. eScholarID:1d18576

1992

  • Moore J, West C, Haylett AA. (1992). Vascular function and tissue injury in murine skin following hyperthermia and photodynamic therapy, alone and in combination. Br J Cancer, 66( 6), 1037-43. eScholarID:1d18577

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