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School of Medicine

Dr Stephen D'Souza MB, ChB, PhD, FRCP

Reader in Child Health/Consultant Paediatrician

Division of Human Development, Academic Unit of Child Health, St Mary's Hospital, Hathersage Road, Manchester. M13 0JH
 

Research

Reader in Child Health, University of Manchester and Consultant Paediatrician, St Mary's Hospital, Manchester.
 

Teaching

Clincal Lead, Paediatric Undergraduate Teaching, Central Manchesterand Manchester Children's University Hospitals NHS Trust.
 

Biography

1970-1973, Clinical Tutor, Department of Child Health, University of Manchester and Registrar in Paediatrics, St Mary's Hospital, Manchester

1973-1976, Lecturer, Department of Child Health, University of Manchester and Senior Registrar in Paediatrics, St Mary's Hospital, Manchester.

1976-1994, Senior Lecturer, Department of Child Health, University of Manchester and Consultant Paediatrician, St Mary's Hospital, Manchester.

 

Qualifications

MB ChB  1964

DCH       1967

MRCP     1969

PhD        1973

FRCP      1983

FCRPCH  1997

 

Publications

2009

  • Iruloh C, D'Souza SW, Fergusson W, Baker PN, Sibley CP, Glazier JD. (2009). Amino acid transport systems beta and A in fetal T lymphocytes in intrauterine growth restriction and with tumor necrosis factor-alpha treatment. Pediatr Res, 65( 1), 51-56. eScholarID:1d19620 | DOI:10.1203/PDR.0b013e31818a0793

2007

  • Clark JM, Hulme E, Devendra Kumar V, Turner MMA, Baker PN, Sibley CP, D'Souza SW. (2007). Effect of maternal asthma on birthweight and neonatal outcome in a British inner city population. Journal of Paediatric and Perinatal Epidemiology, 21, 154-162. eScholarID:1d27025

2006

  • Miles J, Sugumar K, Macrory F, Sims DG, D'Souza SW. (2006). Methadone exposed newborn infants: Outcome after alterations to a service for mothers and infants. Child: Care, Health and Development 2006 (in press, peer reviewed), In Press 2006, eScholarID:1d13074
  • Settle P, Sibley CP, Doughty I, Johnston T, Glazier JD, Powell T, Jansson T, D'Souza SW. (2006). Placental lactate transporter activity and expression in intrauterine growth restriction. J Soc Gynecol Investig, 13( 5), 357-63. eScholarID:1d20265 | DOI:10.1016/j.jsgi.2006.04.006
  • Settle P, Sibley CP, Doughty IM, Johnston T, Glazier JD, Powell TL, Jansson T, D'Souza SW. (2006). Placental lactate transporter expression and activity in intrauterine growth restriction. Journal of the Society for Gynecologic Investigation, 13(5), 357-363. eScholarID:1d13069

2005

  • Sibley, CP, Turner, M, Cetin, I, Ayuk, P, Boyd, C, D'Souza, SW, Glazier, JD, Greenwood, SL., Jansson, T, Powell, T. (2005). Placental phenotypes of intrauterine growth. Pediatr Res, 58( 5), 827-32. eScholarID:1d20271 | DOI:10.1203/01.PDR.0000181381.82856.23

2004

  • Speake PF, Zipitis C, Houston A, D'Souza SW. (2004). Taurine transport into fetal cord blood cells: inhibition by cyclosporin A. JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION, 11, 472-477. eScholarID:1d25445

2003

  • Speake PF, Glazier JD, Ayuk P, Reade M, Sibley CP, D'Souza SW. (2003). L-Arginine transport across the basal plasma membrane of the syncytiotrophoblast of the human placenta from normal and preeclamptic pregnancies. J Clin Endocrinol Metab, 88( 9), 4287-92. eScholarID:1d20283

2002

  • Agarwal R, Chiswick ML, Taylor GM, McNally RJQ, Alston RD, Rimmer S, D'Souza SW. (2002). Antenatal steroids are associated with a reduction in the incidence of cerebral white matter lesions in very low birthweight infants. Archives of Diseases in Childhood, 86, F96-F101. eScholarID:1d3796
  • Ayuk P, Theophanous D, D'Souza SW, Sibley CP, Glazier JD. (2002). L-arginine transport by the microvillous plasma membrane of the syncytiotrophoblast from human placenta in relation to nitric oxide production: effects of gestation, preeclampsia, and intrauterine growth restriction. J Clin Endocrinol Metab, 87( 2), 747-51. eScholarID:1d20282

2000

  • Ayuk P, Sibley CP, Donnai PP, D'Souza SW, Glazier JD. (2000). Development and polarization of cationic amino acid transporters and regulators in the human placenta. Am J Physiol Cell Physiol, 278( 6), C1162-71. eScholarID:1d20284

1999

  • Harrington B, Glazier JD, D'Souza SW, Sibley CP. (1999). System A amino acid transporter activity in human placental microvillous membrane vesicles in relation to various anthropometric measurements in appropriate and small for gestational age babies. Pediatr Res, 45( 6), 810-4. eScholarID:1d20286

1997

  • Sibley CP, Glazier JD, D'Souza SW. (1997). Placental transporter activity and expression in relation to fetal growth. Exp Physiol, 82( 2), 389-402. eScholarID:1d20295

1995

  • Sibley CP, D'Souza SW, Doughty IM, Boyd RDH, Glazier JD, Kuruvilla A, Mahendran D. (1995). Birthweight and sodium/proton exchanger activity in the term human placenta. Placenta, 16( 5), 469-70. eScholarID:1d20301

1994

  • Kuruvilla A, D'Souza SW, Glazier JD, Mahendran D, Maresh MJA, Sibley CP. (1994). Altered activity of the system A amino acid transporter in microvillous membrane vesicles from placentas of macrosomic babies born to diabetic women. J Clin Invest, 94( 2), 689-95. eScholarID:1d20304 | DOI:10.1172/JCI117386
  • Mahendran D, Byrne S, Donnai PP, D'Souza SW, Glazier JD, Jones CJP, Sibley CP. (1994). Na+ transport, H+ concentration gradient dissipation, and system A amino acid transporter activity in purified microvillous plasma membrane isolated from first-trimester human placenta: comparison with the term microvillous membrane. Am J Obstet Gynecol, 171( 6), 1534-40. eScholarID:1d20303

1993

  • Mahendran D, Donnai PP, Glazier JD, D'Souza SW, Boyd RDH, Sibley CP. (1993). Amino acid (system A) transporter activity in microvillous membrane vesicles from the placentas of appropriate and small for gestational age babies. Pediatr Res, 34( 5), 661-5. eScholarID:1d20308

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