Skip to main content Skip to navigation

[University home]

School of Medicine

Professor Martin Gibson MD PhD FRCP

Photograph of Martin Gibson

Honorary Professor/Consultant in Diabetes/Endocrinology: Imaging, Genomics and Proteomics Research Group

Northwest Diabetes Local Research Network
Room B202
Clinical Sciences Building
Salford Royal NHS Foundation Trust
Salford
M6 8HD

 

Role

  • Director of the Greater Manchester Comprehensive Research Network
  • Clinical Lead for the Northwest Diabetes Research Network.
  • Lead for the Vascular (Diabetes and Renal) Research Group at Salford Royal NHS Foundation Trust
  • Consultant Physician (Diabetes and Endocrinology)
 

Research

I am co-lead of the steering committee of the Institute of Health Sciences Diabetes and Obesity Research Network.
My research interests in this area include:

  • The processes by which insulin resistance and glucose intolerance predispose individuals to premature macrovascular disease focusing on the role of the insulin-like growth factor (IGF) system. This spans epidemiological, clinical and molecular relationships between IGF system components and factors influencing the development of cardiovascular disease in diabetic and insulin resistant states.
  • The development novel interventions across primary and secondary care to measure and optimise lipid lowering, antihypertensive and hypoglycaemic therapy utilizing district-wide electronic patient information systems to target and monitor intervention programmes. This includes the development of a proactive call-centre based diabetes management system - the first of its kind in the UK.
  • Linkage of advanced informatics systems with a parallel DNA and serum/plasma repository in order to facilitate future genomic, proteomic and metabonomic studies linked to patient phenotype and pharmacological therapy.
  • An active commercial clinical trials unit with 8-12 ongoing trials at any one time.

Salford has extensive population-based electronic longitudinal data on over 10000 patients with diabetes stretching back to 1993. A sample collection of plasma/serum and DNA is being developed with over 3000 donations from people with diabetes and chronic kidney disease already archived.

Keywords

  • Basic Science
  • Chronic disease management
  • Epidemiology
  • Micro-vascular problems (eg nephropathy, retinopathy, neuropathy)
  • Genetics
  • Macro-vascular complications of diabetes
  • Metabolic syndrome/insulin resistance
  • Patient self-management
 

Methodological Knowledge

  • Audit/Evaluation
  • Basic Sciences Methods
  • Case control studies
  • Clinical Trials
  • Cohort studies
  • Epidemiology/Genomics
  • Randomised control trials/experimental studies

I have regular GCP/ICH training.

 

Publications

2011

  • Deaton, C., Mamas, M., Rutter, M., Gibson, M., Bowell, S., Byrne, R., Coezy, K., Gow, J. & Williams, S (2011). Glucose and insulin abnormalities in patients with heart failure. Eur J Cardiovasc Nurs, eScholarID:151191 | DOI:S1474-5151(10)00116-7 [pii] 10.1016/j.ejcnurse.2010.08.007
  • Hoefield, R., Kalra, P., Baker, P., Sousa, I., Diggle, P., Gibson, M., O'Donoghue, D., Middleton, R. & New, J (2011). The use of eGFR and ACR to predict decline in renal function in people with diabetes. Nephrol Dial Transplant, 26(3), 887-92. eScholarID:138836 | PMID:20837749 | DOI:10.1093/ndt/gfq526
  • Rutter, M., Prais, H., Charlton-Menys, V., Gittins, M., Roberts, C., Davies, R., Moorhouse, A., Jinadev, P., France, M., Wiles, P., Gibson, J., Dean, J., Kalra, P., Cruickshank, J. & Durrington, P (2011). Protection Against Nephropathy in Diabetes with Atorvastatin (PANDA): a randomized double-blind placebo-controlled trial of high- vs. low-dose atorvastatin(1). Diabet Med, 28(1), 100-8. eScholarID:151189 | DOI:10.1111/j.1464-5491.2010.03139.x
  • Siddals, K., Allen, J., Sinha, S., Canfield, A., Kalra, P. & Gibson, J (2011). Apposite insulin-like growth factor (IGF) receptor glycosylation is critical to the maintenance of vascular smooth muscle phenotype in the presence of factors promoting osteogenic differentiation and mineralization. J Biol Chem, 286(19), 16623-30. eScholarID:138835 | PMID:21454560 | DOI:10.1074/jbc.M110.202929
  • Stack, R., Bundy, C., Elliott, R., New, J., Gibson, J. & Noyce, P (2011). Patient perceptions of treatment and illness when prescribed multiple medicines for co-morbid type 2 diabetes. Diabetes Metab Syndr Obes, 4, 127-35. eScholarID:151188 | DOI:10.2147/DMSO.S17444 dmso-4-127 [pii]
  • Tierney, S., Elwers, H., Sange, C., Mamas, M., Rutter, M., Gibson, M., Neyses, L. & Deaton, C (2011). What influences physical activity in people with heart failure? A qualitative study. Int J Nurs Stud, eScholarID:151186 | DOI:S0020-7489(11)00093-9 [pii] 10.1016/j.ijnurstu.2011.03.003
  • Tierney, S., Mamas, M., Skelton, D., Woods, S., Rutter, M., Gibson, M., Neyses, L. & Deaton, C (2011). What can we learn from patients with heart failure about exercise adherence? A systematic review of qualitative papers. Health Psychol, 30(4), 401-10. eScholarID:151190 | DOI:2011-08650-001 [pii] 10.1037/a0022848
  • Tierney, S., Mamas, M., Woods, S., Rutter, M., Gibson, M., Neyses, L. & Deaton, C (2011). What strategies are effective for exercise adherence in heart failure? A systematic review of controlled studies. Heart Fail Rev, eScholarID:151187 | DOI:10.1007/s10741-011-9252-4
  • Narayanan RP, Mason JM, Taylor J, Long AF, Gambling T, New JP, Gibson JM, Young RJ. (2011). Telemedicine to improve glycaemic control: 3-year results from the Pro-Active Call Centre Treatment Support (PACCTS) trial. Diabet Med, Epub ahead of print, eScholarID:140444 | DOI:10.1111/j.1464-5491.2011.03352.x

2010

  • Goodacre, J., Gibson, M., Wilson, K., Alfirevic, Z., Farrar, M. & Darbyshire, J (2010). Improved UK clinical trial capacity through the North West Exemplar Programme. Nat Med, 16(5), 516. eScholarID:151193 | DOI:10.1038/nm0510-516
  • Mamas, M., Deaton, C., Rutter, M., Yuille, M., Williams, S., Ray, S., New, J., Gibson, J. & Neyses, L (2010). Impaired glucose tolerance and insulin resistance in heart failure: underrecognized and undertreated? J Card Fail, 16(9), 761-8. eScholarID:151194 | DOI:10.1016/j.cardfail.2010.05.027
  • Stack, R., Bundy, C., Elliott, R., New, J., Gibson, M. & Noyce, P (2010). Intentional and unintentional non-adherence in community dwelling people with type 2 diabetes: the effect of varying numbers of medicines. The British Journal of Diabetes & Vascular Disease, 10(3), 148-152. eScholarID:151195 | DOI:10.1177/1474651409357034

2009

  • Oldroyd, J., Heald, A., Bansal, N., Vyas, A., Siddals, K., Gibson, M., Clayton, P. & Cruickshank, J (2009). Inflammatory markers and growth in South Asian and European origin infants in Britain: the Manchester Children's Growth and Vascular Health Study. Atherosclerosis, 207(1), 227-31. eScholarID:138837 | PMID:19439300 | DOI:10.1016/j.atherosclerosis.2009.03.045

2008

  • Forbes K, Hurst LM, Aplin JD, Westwood M, Gibson JM. (2008). Statins are detrimental to human placental development and function; use of statins during early pregnancy is inadvisable. Journal of Cellular and Molecular Medicine, 12(6A), 2295-6. eScholarID:138838 | DOI:10.1111/j.1582-4934.2008.00466.x

2007

  • Betteridge D, Gibson JM. (2007). Effects of rosuvastatin on lipids, lipoproteins and apolipoproteins in the dyslipidaemia of diabetes. Diabet Med, 24(5), 541-9. eScholarID:1d17782 | DOI:10.1111/j.1464-5491.2007.02095.x
  • Dark PM, Buchan IE, Warhurst G, New JP, Gibson JM, A Ridetsky, Pat Baker, Brass AA. (2007). Lipid metabolism and outcome from critical illness. Intensive Care Medicine, eScholarID:1d14379
  • Heald, A, Anderson, SG, Patel, J, Rudenski, A, Yates, A, Hughes, E, Prabakharan, D, Reddy, S, Durrington, PN, Gibson, JM, Cruickshank, (K, Laing, I. (2007). Change in pancreatic beta-cell function (HOMA-B) varies in different populations with similar genetic backgrounds but different environments. Diabetic Medicine, 24(2), 145-53. eScholarID:1d27494
  • Heald, A, Patel, J, Anderson, S, Vyas, A, Rudenski, A, Hughes, E, Panja, N, Ullah, A, Prabhakaran, D, Reddy, S, Durrington, PN, Gibson, JM, Laing, I, Bhatnagar, D, Cruickshank, (K. (2007). Migration is associated with lower total, but not free testosterone levels in South Asian men. Clin Endocrinol (Oxf), 67(5), 651-5. eScholarID:1d17781 | DOI:10.1111/j.1365-2265.2007.02856.x
  • Salonen, J, Uimari, P, Aalto, J, Pirskanen, M, Kaikkonen, J, Todorova, B, Hypponen, J, Korhonen, V, Asikainen, J, Devine, C, Tuomainen, T, Luedemann, J, Nauck, M, Kerner, W, Stephens, RH, New, JP, Ollier, WER, Gibson, JM, Payton, A, Horan, M A, Pendleton, N, Mahoney, W, Meyre, D, Delplanque, J, Froguel, P, Luzzatto, O, Yakir, B, Darvasi, A. (2007). Type 2 Diabetes Whole-Genome Association Study in Four Populations: The DiaGen Consortium. Am J Hum Genet, 81(2), 338-45. eScholarID:1d16155 | DOI:10.1086/520599
  • Dark PM, Buchan IE, Warhurst G, New JP, Gibson JM, Baker PP.G, Steve Kemp, Brass AA. (2007). Early and sustained acute falls in total serum cholesterol are associated with critical illness mortality in the setting of tight glycaemic control. Inflammation Research, 53, S253-4. eScholarID:17d951

2006

  • Castleden HA, Shields B, Bingley PJ, Williams AJ, Sampson M, Walker, MG, Gibson, JM, McCarthy MI, Hitman GA, Levy JC, Hattersley AT, Vaidya B, Pearson ER. (2006). GAD antibodies in probands and their relatives in a cohort clinically selected for Type 2 diabetes. Diabetic Medicine, 23(8), 834-8. eScholarID:1d27342
  • Heald A, Kaushal K, Siddals KW, Rudenski A, Anderson S, Gibson JM. (2006). Insulin-like growth factor binding protein-2 (IGFBP-2) is a marker for the metabolic syndrome. Experimental Clinical Endocrinology and Diabetes, 114(7), 371-6. eScholarID:1d27340
  • Heald A, Stephens RH, Gibson JM. (2006). The insulin-like growth factor system and diabetes - an overview. Diabetic Medicine, 23:1, 19-24. eScholarID:1d27037
  • Heald, A, Karvestedt L, Anderson SG, McLaughlin J, Knowles A, Wong L, Grill V, Cruickshank, (K, White, A, Gibson, JM, Brismar K. (2006). Low insulin-like growth facctor-II levels predict weight gain in normal weight subjects with type 2 diabetes. American Journal Of Medicine, 119(2), 167.e9-15. eScholarID:1d27039
  • Middleton RJ, Foley RN, Hegarty J, Cheung CM, McElduff P, Gibson JM, Kalra PA, O'Donoghue D, New JP. (2006). The unrecognized prevalence of chronic kidney disease in diabetes. Nephrol Dial Transplant, 21(1), 88-92. eScholarID:1d11997

2005

  • Middleton RJ, Foley RN, Gibson JM, O'Donoghue D, New JP. (2005). The prevalence and risk factors for anaemia in a population with diabetes mellitus. Diabetes. ( 54, pp. A203-A204). eScholarID:3d1057
  • Betteridge DJ, Gibson JM, Sager P. (2005). Effect of rosuvastatin and atorvastatin on CRP levels in patients with type 2 diabetes: Results from the Andromeda Study. eScholarID:2d1930
  • Gibson JM, Middleton RJ, Foley, McElduff P, O'Donoghue D, New JP. (2005). The unrecognised prevalence of chronic kidney disease in patients with diabetes. eScholarID:2d2506
  • Stephens, RH, McElduff, P, Worthington, J, Ollier, WER, New, JP, Payton, A, Pendleton, N, Horan, M A, Cruickshank, (K, Gibson, JM. (2005). Single-nucleotide polymorphisms (SNPs) in the IGFBP1 gene are associated with diabetes risk and nephropathy in a cohort of type 2 diabetes mellitus patients. eScholarID:2d2022
  • Denniston AK, Banerjee SS, Gibson JM, Dodson PM. (2005). Cardiovascular therapies and their role in diabetic eye disease. Diabetic Medicine, 22(5), 665-6. eScholarID:1d27344
  • Heald A, Anderson S, F Ivison, Riste L, I Laing, Cruickshank (K, Gibson JM. (2005). Low sex hormone binding globulin is a potential marker for the metabolic syndrome in different ethnic groups. Experimental Clinical Endocrinology and Diabetes, 113, 522-528. eScholarID:1d26741
  • Heald A, Kaushal K, Anderson S, M Redpath, Durrington PN, Selby PL, Gibson JM. (2005). Effects of hormone replacement therapy on insulin-like growth factor (IGF)-I, IGF-II and IGF binding protein (IGFBP)-1 ti IGFBP-4: implications for cardiovascular risk. Gynaecological Endocrinology, 8, 620-627. eScholarID:1d26737
  • Heald, A, Anderson, S, Vyas, A, Siddals, KW, Patel, J, Yates AP, Bhatnagar, D, Prabhakaran D, Hughes, E, Rudenski, A, Durrington, PN, Gibson, JM, Cruickshank, (K. (2005). Marked differences in the IGF-system associated with migration in comparable populations of Gujaratis living in Sandwell UK and Gujarat India. Diabetologia, 48(9), 1756-65. eScholarID:1d26505
  • Heald, A, Sharma, R, Anderson, S, Vyas, A, Siddals, KW, J Patel, Bhatnagar, D, D Prabharkaran, Rudenski, A, E Hughes, Durrington, PN, Gibson, JM, Cruickshank, (K. (2005). Dietary intake and the insulin-like growth factor system: effects of migration in two related populations in India and Britain with markedly different dietary intake. Public Health Nutrition, 8, 620-627. eScholarID:1d26739
  • Mason J, Freemantle N, Gibson JM, New JP. (2005). Specialist nurse-led clinics to improve control of hypertension and hyperlipidemia in diabetes: economic analysis of the SPLINT trial. Diabetes Care, 28( 1), 40-6. eScholarID:1d12012
  • Mishra M, Durrington PN, Mackness MI, Siddals KW, Kaushal K, Davies R, Gibson JM, Ray DW. (2005). The effect of atorvastatin on serum lipoproteins in acromegaly. Clin Endocrinol (Oxf), 62( 6), 650-5. eScholarID:1d19276 | DOI:10.1111/j.1365-2265.2005.02273.x
  • Mishra M, Durrington PN, Mackness MI, Siddals KW, Kaushal K, Davies R, Gibson JM. (2005). Atorvastatin affects the serum lipoprotein profile and cardiovascular risk in acromegaly. Clinical Endocrinololgy, 62, 650-655. eScholarID:1d14102
  • Stephens RH, McElduff P, Heald A, New JP, Worthington J, Ollier WER, Gibson JM. (2005). Polymorphisms in insulin-like growth factor-binding protein 1 are associated with impaired renal function in Type-2 diabetes mellitus. Diabetes, 54(12), 3547-53. eScholarID:1d11934 | DOI:10.2337/diabetes.54.12.3547
  • Young, R, Taylor, J, Friede, T, Hollis, S, Mason, J, Lee, P, Burns, E, Long, A, Gambling, T, New, JP, Gibson, JM. (2005). Pro-active call center treatment support (PACCTS) to improve glucose control in type 2 diabetes: a randomized controlled trial. Diabetes Care, 28( 2), 278-82. eScholarID:1d12011 | DOI:10.2337/diacare.28.2.278

2004

  • Heald A, C Golding, Sharma R, Siddals KW, C Lawton, Anderson S, Gibson JM, J E Cade. (2004). A substitution model of dietary manipulation is an effective means of optimising lipid profile, reducing C-reactive protein and increasing insulin-like growth factor-1. British Journal of Nutrition, 92, 809-818. eScholarID:1d26743
  • Kaushal K, Heald A, Siddals KW, Sandhu MS, Dunger DB, Gibson JM, Wareham NJ. (2004). The impact of abnormalities in IGF and inflammatory systems on the metabolic syndrome. Diabetes Care, 27(11), 2682-8. eScholarID:1d10000
  • Khan A, Talbot J, Tieszen KL, Gardner E, Gibson JM, New JP. (2004). Evaluation of a bedside blood ketone sensor: the effects of acidosis, hyperglycaemia and acetoacetate on sensor performance. Diabet Med, 21(7), 782-5. eScholarID:1d10014
  • Siddals K, Marshman E, Westwood M, Gibson JM. (2004). Abrogation of insulin-like growth factor-I (IGF-I) and insulin action by mevalonic acid depletion. Journal of Biological Chemistry, 279 (37), 38353-38359. eScholarID:1d10165
  • Siddals KW, Marshman E, Westwood M, Gibson JM. (2004). Abrogation of insulin-like growth factor-I (IGF-I) and insulin action by mevalonic acid depletion: synergy between protein prenylation and recep glycosylation pathways. J Biol Chem, 279(37), 38353-9. eScholarID:1d10003
  • Kaushal K, Bhatacharyya A, Gibson JM, Varghese B, Davis JRE. (2004). Adequacy of information delivered to patients during consultation for thyrotoxicosis. Clinical Endocrinology, 61, 778-782. eScholarID:17d488
  • New JP, Mason JM, Freemantle N, Teasdale S, Wong L, Bruce NJ, Burns JA, Gibson JM. (2004). Educational outreach in diabetes to encourage practice nurses to use primary care hypertension and hyperlipidaemia guidelines (EDEN): a randomized controlled trial. Diabet Med, 21(6), 599-603. eScholarID:17d308
  • Sandhu MS, Gibson JM, Heald A, Dunger DB, Wareham NJ. Association between insulin-like growth factor-I: insulin-like growth factor-binding protein-1 ratio and metabolic and anthropometric factors in men and women, Cancer Epidemiol Biomarkers and Prevention. 2004. 166-70113(1). eScholarID:19d100

2003

  • Heald A, Anderson S, Ivison F, Laing I, Gibson JM, Cruickshank (K. (2003). C-reactive protein and the insulin-like growth factor (IGF)-system in relation to risk of cardiovascular disease in different ethnic groups. Atherosclerosis, 170(1), 79-86. eScholarID:1d7056
  • Heald A, Ivison F, Anderson S, Cruickshank (K, Laing I, Gibson JM. (2003). Significant ethnic variation in total and free testosterone concentration. Clin Endocrinol (Oxf), 58(3), 262-6. eScholarID:1d7062
  • Kaushal K, Gibson JM, Railton A, Hounsome B, New JP, Young RJ. (2003). A protocol for improved glycaemic control following corticosteroid therapy in diabetic pregnancies. Diabet Med, 20(1), 73-5. eScholarID:1d2962
  • New JP, Mason JM, Freemantle N, Teasdale S, Wong LM, Bruce NJ, Burns JA, Gibson JM. (2003). Specialist nurse-led intervention to treat and control hypertension and hyperlipidemia in diabetes (SPLINT): a randomized controlled trial. Diabetes Care, 26(8), 2250-5. eScholarID:1d7057
  • Sandhu MS, Gibson JM, Heald A, Dunger DB, Wareham NJ. (2003). Low circulating IGF-II concentrations predict weight gain and obesity in humans. Diabetes, 52(6), 1403-8. eScholarID:1d7060 | DOI:10.2337/diabetes.52.6.1403
  • Khan, ASA, Soop, M, Rooyakers O, Kaushal, K, Gardner, E, Tieszen KL, Ljungqvist O, New, JP, Gibson, JM, Gordon Carlson. (2003). Endotoxin-induced protein catabolism in man is closely related to the proinflammatory cytokine response. Clin Nutr, 22(S1), S43. eScholarID:17d595

2002

  • Heald, A., Siddals, K., Fraser, W., Taylor, W., Kaushal, K., Morris, J., Young, R., White, A. & Gibson, J (2002). Low circulating levels of insulin-like growth factor binding protein-1 (IGFBP-1) are closely associated with the presence of macrovascular disease and hypertension in type 2 diabetes. Diabetes, 51(8), 2629-2636. eScholarID:151215
  • MS Sandhu, Heald A, Gibson JM, Cruickshank (K, DB Dunger, NJ Wareham. (2002). Circulating concentrations of insulin-like growth factor-1 and the development of glucose intolerance: a prospective observational study. The Lancet, 359, 1740-1745. eScholarID:1d2623 | DOI:10.1016/S0140-6736(02)08655-5
  • Siddals, K., Westwood, M., Gibson, J. & White, A (2002). IGF-binding protein-1 inhibits IGF effects on adipocyte function: implications for insulin-like actions at the adipocyte. Journal of Endocrinology, 174(2), eScholarID:151214
  • Soop, M, Duxbury, H, Agwunobi, A, Gibson, JM, Hopkins, SJ, Childs, C, Cooper, RG, Maycock, PF, Little, RA, Carlson, GL. (2002). Euglycemic hyperinsulinemia augments the cytokine and endocrine responses to endotoxin in humans. Am J Physiol Endocrinol Metab, 282( 6), E1276-85. eScholarID:1d14221

2001

  • Bajoria RR, Gibson JM, S Ward, Sooranna SR, Neilson JP, Westwood M. (2001). Placental regulation of insulin-like factor axis in monochorionic twins with chronic twin-twin transfusion syndrome. Journal of Clinical Endocrinology and Metabolisdm, 86, 3150-3156. eScholarID:1d3735
  • Cruickshank, J., Heald, A., Anderson, S., Cade, J., Sampayo, J., Riste, L., Greenhalgh, A., Taylor, W., Fraser, W., White, A. & Gibson, J (2001). Epidemiology of the insulin-like growth factor system in three ethnic groups. American Journal of Epidemiology, 154(6), 504-513. eScholarID:151209
  • Gibson, J., Aplin, J., White, A. & Westwood, M (2001). Regulation of IGF bioavailability in pregnancy. Molecular Human Reproduction, 7(1), 79-87. eScholarID:151223
  • Heald, A., Cruickshank, J., Riste, L., Cade, J., Anderson, S., Greenhalgh, A., Sampayo, J., Taylor, W., Fraser, W., White, A. & Gibson, J (2001). Close relation of fasting insulin-like growth factor binding protein-1 (IGFBP-1) with glucose tolerance and cardiovascular risk in two populations. Diabetologia, 44(3), 333-339. eScholarID:151212
  • Westwood M, Aplin JD, IA Collinge, Gill A, White A, Gibson JM. (2001). Alpha 2-Macroglobulin: a new component in the insulin-like growth factor/insulin-like growth factor binding protein-1 axis. Journal of Biological Chemistry, 276 (45), 41668-41674. eScholarID:1d2387 | DOI:10.1074/jbc.M102793200
  • Westwood M, Gibson JM, Sooranna SR, Ward BS, Neilson JP, Bajoria RR. (2001). Gene or placenta as modulator of fetal growth? Evidence from the insulin-like growth factor axis in twins with discordant growth. Molecular Human Reproduction, 7, 387-395. eScholarID:1d7506

2000

  • Heald, A., Selby, P., White, A. & Gibson, J (2000). Progestins abrogate estrogen-induced changes in the insulin-like growth factor axis. American Journal of Obstetrics and Gynecology, 183(3), 593-600. eScholarID:151220
  • Jenkins, R., Valcavi, R., Zini, M., Frasoldati, A., Heller, S., Camacho-Hubner, C., Gibson, J., Westwood, M. & Ross, R (2000). Association of elevated insulin-like growth factor binding protein-1 with insulin resistance in hyperthyroidism. Clinical Endocrinology, 52(2), 187-195. eScholarID:151207
  • R Blakytny, EB Jude, Gibson JM, Boulton AJM, Ferguson MW.J. (2000). Lack of insulin-like growth factor 1 (IGF1) in the basal keratinocyte layer of diabetic skin and diabetic foot ulcers. Journal Of Pathology, 190, 589-596. eScholarID:1d33879

1999

  • Gibson, J., Westwood, M., Lauszus, F., Klebe, J., Flyvbjerg, A. & White, A (1999). Phosphorylated insulin-like growth factor binding protein 1 is increased in pregnant diabetic subjects. Diabetes, 48(2), 321-326. eScholarID:151219
  • Westwood, M., Gibson, J., Pennells, L. & White, A (1999). Modification of plasma insulin-like growth factors and binding proteins during oral contraceptive use and the normal menstrual cycle. American Journal of Obstetrics and Gynecology, 180(3), 530-536. eScholarID:151218

1998

  • Stearne, et al (1998). Cost effectiveness analysis of improved blood pressure control in hypertensive patients with type 2 diabetes: UKPDS 40. British Medical Journal, 317(7160), 720-726. eScholarID:151210
  • Stearne, et al (1998). Efficacy of atenolol and captopril in reducing risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 39. British Medical Journal, 317(7160), 713-720. eScholarID:151211
  • Stearne, et al (1998). Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. British Medical Journal, 317(7160), 703-713. eScholarID:151225

1997

  • Westwood, M., Gibson, J. & White, A (1997). Purification and characterization of the insulin-like growth factor-binding protein-1 phosphoform found in normal plasma. Endocrinology, 138(3), 1130-1136. eScholarID:151221

1996

  • Gibson, J., Westwood, M., Young, R. & White, A (1996). Reduced insulin-like growth factor binding protein-1 (IGFBP-1) levels correlate with increased cardiovascular risk in noninsulin dependent diabetes mellitus (NIDDM). Journal of Clinical Endocrinology & Metabolism, 81(2), 860-863. eScholarID:151222

1995

  • Gibson, J., Westwood, M., Crosby, S., Gordon, C., Holly, J., Fraser, W., Anderson, C., White, A. & Young, R (1995). Choice of Treatment Affects Plasma-Levels of Insulin-Like Growth Factor-Binding Protein-1 in Noninsulin-Dependent Diabetes-Mellitus. Journal of Clinical Endocrinology & Metabolism, 80(4), 1369-1375. eScholarID:151205
  • Westwood, M., Gibson, J., Williams, A., Clayton, P., Hamberg, O., Flyvbjerg, A. & White, A (1995). Hormonal-Regulation of Circulating Insulin-Like Growth Factor-Binding Protein-Phosphorylation Status. Journal of Clinical Endocrinology & Metabolism, 80(12), 3520-3527. eScholarID:151213

1994

  • Westwood, M., Gibson, J., Davies, A., Young, R. & White, A (1994). The Phosphorylation Pattern of Insulin-Like Growth Factor-Binding Protein-1 in Normal Plasma Is Different from That in Amniotic-Fluid and Changes During Pregnancy. Journal of Clinical Endocrinology & Metabolism, 79(6), 1735-1741. eScholarID:151224

1993

  • Crosby, S., Anderton, C., Westwood, M., Holly, J., Hughes, S., Gibson, M., Morrison, C., Young, R. & White, A (1993). Measurement of Insulin-Like Growth Factor-Ii in Human Plasma Using a Specific Monoclonal Antibody-Based 2-Site Immunoradiometric Assay. Journal of Endocrinology, 137(1), 141-150. eScholarID:151216

1986

  • Milner, N., Nali, M., Gibson, J. & Rees, H (1986). Early Stages of Ecdysteroid Biosynthesis - the Role of 7-Dehydrocholesterol. Insect Biochemistry, 16(1), 17-23. eScholarID:151208

1984

  • Gibson, J., Isaac, R., Dinan, L. & Rees, H (1984). Metabolism of [H-3] Ecdysone in Schistocerca-Gregaria - Formation of Ecdysteroid Acids Together with Free and Phosphorylated Ecdysteroid Acetates. Archives of Insect Biochemistry and Physiology, 1(4), 385-407. eScholarID:151217

1983

  • Gibson, J., Majumder, M., Mendis, A. & Rees, H (1983). Absence of Phytosterol Dealkylation and Identification of the Major Ecdysteroid as Makisterone-a in Dysdercus-Fasciatus (Heteroptera, Pyrrhocoridae). Archives of Insect Biochemistry and Physiology, 1(1), 105-120. eScholarID:151206

Top of page

| Skip to main content | Skip to navigation | Skip to Search |