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School of Medicine

Professor Andrew Pickles 

Photograph of Andrew Pickles

Professor of Epidemiological and Social Statistics

1.307 Jean McFarlane Building, University Place

 

Role

Professor of Epidemiological and Social Statistics. Founder of the Developmental Psychopathology Group within the Neuroscience Research Institute. Postgraduate Research Tutor.


 

 

Research

Longitudinal methods particularly in the field of developmental psychopathology and child development.

Survey research methods, in particular the use of missing data by design.

Frailty modelling of event data, more recently recognizing recall error.

Models for biometrical and molecular genetic studies, particularly of behaviour and of autism.

Latent variable modelling of non-normal data - this is collaborative work with Sophia Rabe-Hesketh and Anders Skrondal on Generalized Linear Latent and Mixed Models; the Stata gllamm procedure. For further information and downloads on gllamm

Measurement and diagnosis of autism

Trends in child and adolescent mental health

Founder and co-organiser of the Developmental Psychopathology Group within the Neuroscience Research Institute.

Personal downloads page.

 

Teaching

Short courses in advanced statistical analysis:

Longitudinal data Analysis, Design and Analysis of Complex Surveys, Structural Equation Modelling (SEM) in Mplus, Causal Analysis in Stata, Generalized Linear Latent and Mixed Modelling. 

 

Collaborators and affiliated staff

Collaborators

  • Jonathan Hill
    University of Manchester
    Developmental mechanisms in depression and emotional regulation
  • Barbara Maughan and Michal Rutter
    Institute of Psychiatry, London
    Child psychiatric epidemiology: trends and continuities in mental healt
  • Catherine Lord
    University of Michigan
    Diagnosis and development of autism
  • Tony Charman, Institute of Child health, UCL. Gillian Baird, Guy's Hospital & Emily Simonoff, Institute of Psychiatry, London. Special Needs and Autism Project (SNAP)
  • Mark Johnson and Mayada Elsabagh, BASIS - autism sibs network 
  • Tony Bailey and Tony Monaco
    University of Oxford
    Genetics of autism
  • Professor Gina Conti-Ramsden
    Speech and Language Pathology
    Familial and genetic basis of specific language impairment
  • Dr Jonathan Green
    Child and Adolescent Psychiatry
    Treatment trial for autism 
  • Adnan Custovic, Angela Simpson and Jackie Smith, Respiratory Medicine, Manchester Asthma and Allergy Study
  • Azza Aglan and Mike Kerfoot, Psychology and Psychiatry, Manchester, Self-Harm
  • Roger Webb and Kathryn Abel, Psychiatry, Manchester, Danish population register studies
 

Selected publications

2008

  • Aglan A, Kerfoot M, Pickles A. (2008). Pathways from adolescent deliberate self-poisoning to early adult outcomes: a six-year follow-up. J Child Psychol Psychiatry, 49( 5), 508-15. further details
  • Baird, G, Pickles, A, Simonoff, E, Charman, T, Sullivan, P, Chandler, S, Loucas, T, Meldrum, D, Afzal, M, Thomas, B, Jin, L, Brown, D. (2008). Measles vaccination and antibody response in autism spectrum disorders. Arch Dis Child, further details
  • Falcaro, M, Pickles, A, Newbury, D, Addis, L, Banfield, E, Fisher, S, Monaco, A, Simkin, Z, Conti-Ramsden, GM, NULL. (2008). Genetic and phenotypic effects of phonological short-term memory and grammatical morphology in specific language impairment. Genes Brain Behav, 7(4), 393-402. Full text doi:DOI: 10.1111/j.1601-183X.2007.00364.x further details
  • Gotham K, Pickles A, Lord C. (2008). Standardizing ADOS Scores for a Measure of Severity in Autism Spectrum Disorders. J Autism Dev Disord, Full text doi:10.1007/s10803-008-0674-3 further details

2007

  • Pickles A, B. Maughan, M. Wadsworth. (2007). Epidemiological Methods in Lifecourse Research. Open University Press. further details
  • Chandler S, Charman T, Baird G, Simonoff E, Loucas T, Meldrum D, Scott M, Pickles A. (2007). Validation of the social communication questionnaire in a population cohort of children with autism spectrum disorders. J Am Acad Child Adolesc Psychiatry, 46( 10), 1324-32. further details
  • Collishaw S, Pickles A, Messer J, Rutter M, Shearer C, Maughan B. (2007). Resilience to adult psychopathology following childhood maltreatment: evidence from a community sample. Child Abuse Negl, 31( 3), 211-29. further details
  • Falcaro M, Pickles A. (2007). A flexible model for multivariate interval-censored survival times with complex correlation structure. Stat Med, 10;26(3), 663-680. Full text doi:10.1002/sim.2522 further details
  • Gotham K, Risi S, Pickles A, Lord C. (2007). The Autism Diagnostic Observation Schedule: revised algorithms for improved diagnostic validity. J Autism Dev Disord, 37( 4), 613-27. further details

2006

  • Baird G, Simonoff E, Pickles A, Chandler S, Loucas T, Meldrum D, Charman T. (2006). Prevalence of Disorders of the Autism Spectrum in a Population Cohort of Children in South Thames - the Special Needs and Autism Project (SNAP). Lancet, 15;368(9531), 210-215. Full text doi:10.1016/S0140-6736(06)69041-7  further details
  • Gotham, Risi, Pickles A, Lord. (2006). The Autism diagnostic Observation Schedule (ADOS). Journal of Autism and Developmental Disorders, further details
  • Harrington R, Pickles A, Harrington V, Aglan A, Burroughs H, Kerfoot M. (2006). Early adult outcomes of adolescents who deliberately poisoned themselves. Journal of the American Academy of Child and Adolescent Psychiatry, Full text doi:10.1016/j.schres.2005.07.003 further details
  • Lord C, Risi S, DiLavore P, Shulman C, Thurm A, Pickles A. (2006). Autism from 2 to 9 years of age. Archives of General Psychiatry, 63(6), 694-701. Full text doi:10.1001/archpsyc.63.6.694 further details

2005

  • LiY, Pickles A, SavageM. (2005). Social capital and social trust in Britain. European Sociological Review, 21, 109-123. further details
  • Payton A, Gibbons LC, Davidson YS, Ollier WER, Rabbitt P-, Worthington J, Pickles A, Pendleton N, Horan M A. (2005). Influence of serotonin transporter gene polymorphisms on cognitive decline and cognitive abilities in a nondemented elderly population. Molecular Psychiatry, 10(12), 1133-1139. Full text doi:10.1038/sj.mp.4001733 further details
  • Rabe-Hesketh S, SkrondalA, Pickles A. (2005). Maximum likelihood estimation of limited and discrete dependent variable models with nested random effects. J of Econometrics, 128, 301-323. further details
  • WebbR, AbelK, Pickles A, ApplebyL. (2005). Risks to siblings of psychotic parents review and meta-analysis. Am J Psychiatry, 162(6), 1045-1056. further details

2004

  • Collishaw S, Maughan B, Goodman R, Pickles A. (2004). Time trends in adolescent mental health. J Child Psychol Psychiatry, 45( 8), 1350-62. further details
  • Rabe-HeskethS, SkrondalA, Pickles A. (2004). Generalized multilevel structural equation modeling. Psychometrika, 69, 167-190. Full text doi:10.1007/BF02295939 further details

2003

  • Pickles A. (2003). Missing data: problems and solutions. Encyclopedia of Social Measurement. further details
  • FoleyD.L, NealeM.C, GardnerC.O, Pickles A, KendlerK.S. (2003). Major depression and associated impairment: Same or different genetic and environmental risk factors? American Journal of Psychiatry, further details
  • Pickles A, AngoldA. (2003). Natural categories or fundamental dimensions: On carving nature at the joints and the re-articulation of psychopathology. Development and Psychopathology, further details
  • Rabe-HeskethS, Pickles A, SkrondalA. (2003). Correcting for covariate measurement error in logistic regression using non-parametric maximum likelihood estimation. Statistical Modelling, 3, 215-232. further details

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