Dr Tony Payton 

2011

• Carrol, E., Payton, A., Payne, D., Miyajima, F., Chaponda, M., Mankhambo, L., Banda, D., Molyneux, E., Cox, H., Jacobson, G., Carr, D., Molyneux, M., Stewart, J., Quinn, J., Hart, C. & Ollier, W (2011). The IL1RN promoter rs4251961 correlates with IL-1 receptor antagonist concentrations in human infection and is differentially regulated by GATA-1. J Immunol, 186(4), 2329-35. eScholarID:125805 | PMID:21248262 | DOI:10.4049/jimmunol.1002402
• Davies G, Tenesa A, Payton A, Yang J, Harris SE, Liewald D, Ke X, Le Hellard S, Christoforou A, Luciano M, McGhee K, Lopez L, Gow AJ, Corley J, Redmond P, Fox HC, Haggarty P, Whalley LJ, McNeill G, Goddard ME, Espeseth T, Lundervold AJ, Reinvang I, Pickles A, Steen VM, Ollier W, Porteous DJ, Horan M, Starr JM, Pendleton N, Visscher PM, Deary IJ. (2011). Genome-wide association studies establish that human intelligence is highly heritable and polygenic. Mol Psychiatry, Epub ahead of print, eScholarID:128070 | DOI:10.1038/mp.2011.85
• Jayasekeran, V., Pendleton, N., Holland, G., Payton, A., Jefferson, S., Michou, E., Vasant, D., Ollier, B., Horan, M., Rothwell, J. & Hamdy, S (2011). Val66Met in Brain-Derived Neurotrophic Factor Affects Stimulus-Induced Plasticity in the Human Pharyngeal Motor Cortex. Gastroenterology, Epub ahead of print, eScholarID:125803 | PMID:21699787 | DOI:10.1053/j.gastro.2011.05.047
• Juhasz, G., Dunham, J., McKie, S., Thomas, E., Downey, D., Chase, D., Lloyd-Williams, K., Toth, Z., Platt, H., Mekli, K., Payton, A., Elliott, R., Williams, S., Anderson, I. & Deakin, J (2011). The CREB1-BDNF-NTRK2 Pathway in Depression: Multiple Gene-Cognition-Environment Interactions. Biol Psychiatry, Epub ahead of print, eScholarID:106681 | PMID:21215389 | DOI:10.1016/j.biopsych.2010.11.019
• Lopez, L., Harris, S., Luciano, M., Liewald, D., Davies, G., Gow, A., Tenesa, A., Payton, A., Ke, X., Whalley, L., Fox, H., Haggerty, P., Ollier, W., Pickles, A., Porteous, D., Horan, M., Pendleton, N., Starr, J. & Deary, I (2011). Evolutionary conserved longevity genes and human cognitive abilities in elderly cohorts. Eur J Hum Genet, Epub ahead of print, eScholarID:135837 | PMID:22045296 | DOI:10.1038/ejhg.2011.201
• Mekli, K., Payton, A., Miyajima, F., Platt, H., Thomas, E., Downey, D., Lloyd-Williams, K., Chase, D., Toth, Z., Elliott, R., Ollier, W., Anderson, I., Deakin, J., Bagdy, G. & Juhasz, G (2011). The HTR1A and HTR1B receptor genes influence stress-related information processing. Eur Neuropsychopharmacol, 21(1), 129-39. eScholarID:106680 | PMID:20638825 | DOI:10.1016/j.euroneuro.2010.06.013
• Selvarajah, J., Smith, C., Hulme, S., Georgiou, R., Sherrington, C., Staniland, J., Illingworth, K., Jury, F., Payton, A., Ollier, W., Vail, A., Rothwell, N., Hopkins, S. & Tyrrell, P (2011). Does inflammation predispose to recurrent vascular events after recent transient ischaemic attack and minor stroke? The North West of England transient ischaemic attack and minor stroke (NORTHSTAR) study. Int J Stroke, 6(3), 187-94. eScholarID:125800 | PMID:21557802 | DOI:10.1111/j.1747-4949.2010.00561.x

2010

• Juhasz, G., Downey, D., Hinvest, N., Thomas, E., Chase, D., Toth, Z., Lloyd-Williams, K., Mekli, K., Platt, H., Payton, A., Bagdy, G., Elliott, R., Deakin, J. & Anderson, I (2010). Risk-taking behavior in a gambling task associated with variations in the tryptophan hydroxylase 2 gene: relevance to psychiatric disorders. Neuropsychopharmacology, 35(5), 1109-19. eScholarID:125802 | PMID:20043001 | DOI:10.1038/npp.2009.216
• Mekli, K., Payton, A., Miyajima, F., Platt, H., Thomas, E., Downey, D., Lloyd-Williams, K., Chase, D., Toth, Z., Elliott, R., Ollier, W., Anderson, I., Deakin, J., Bagdy, G. & Juhasz, G (2010). The HTR1A and HTR1B receptor genes influence stress-related information processing. Eur Neuropsychopharmacol, Epub ahead of print, eScholarID:86640 | PMID:20638825 | DOI:10.1016/j.euroneuro.2010.06.013
• Payton A, Miyajima F, Ollier WER, Rabbitt P, Pickles A, Weiss V, Pendleton N, Horan M A. (2010). Investigation of a functional quinine oxidoreductase (NQO2) polymorphism and cognitive decline. Neurobiol Aging, 31(2)(Epub 2008), 351-352. eScholarID:1d17390 | DOI:10.1016/j.neurobiolaging.2008.04.014

2009

• Juhasz, G., Chase, D., Pegg, E., Downey, D., Toth, Z., Stones, K., Platt, H., Mekli, K., Payton, A., Elliott, R., Anderson, I. & Deakin, J (2009). CNR1 gene is associated with high neuroticism and low agreeableness and interacts with recent negative life events to predict current depressive symptoms. Neuropsychopharmacology, 34(8), 2019-27. eScholarID:125801 | PMID:19242408 | DOI:10.1038/npp.2009.19
• Lind, P, Luciano, M, Horan, M A, Marioni, R, Wright, M, Bates, T, Rabbitt, P, Harris, S, Davidson, YS, Deary, I, Gibbons, LC, Pickles, A, Ollier, WER, Pendleton, N, Price, J, Payton, A, Martin, N. (2009). No Association Between Cholinergic Muscarinic Receptor 2 (CHRM2) Genetic Variation and Cognitive Abilities in Three Independent Samples. Behav Genet, 39(5), 513-523. eScholarID:1d19095 | DOI:10.1007/s10519-009-9274-z
• Luciano, M, Miyajima, F, Lind, P, Bates, T, Horan, M, Harris, S, Wright, M, Ollier, WER, Hayward, C, Pendleton, N, Gow, A, Visscher, P, Starr, J, Deary, I, Martin, N, Payton, A. (2009). Variation in the dysbindin gene and normal cognitive function in three independent population samples. Genes Brain Behav, 8(2), 218-227. eScholarID:1d18675 | DOI:10.1111/j.1601-183X.2008.00462.x
• Payton A, Payne D, Mankhambo L, Banda D, Hart C, Ollier WER, Carrol E. (2009). Nitric oxide synthase 2A (NOS2A) polymorphisms are not associated with invasive pneumococcal disease. BMC Med Genet, 10, eScholarID:1d18956 | DOI:10.1186/1471-2350-10-28

2008

• Ashworth JJ, Smyth JV, Pendleton N, Horan M A, Payton A, Worthington J, Ollier WER, Ashcroft GG. (2008). Polymorphisms spanning the 0N exon and promoter of the estrogen receptor-beta (ERbeta) gene ESR2 are associated with venous ulceration. Clin Genet, 73 (1), 55-61. eScholarID:1d16791
• Luciano, M, Lind, P, Deary, I, Payton, A, Posthuma, D, Butcher, L, Bochdanovits, Z, Whalley, L, Visscher, P, Harris, S, Polderman, T, Davis, O, Wright, M, Starr, J, de Geus, E, Bates, T, Montgomery, G, Boomsma, D, Martin, N, Plomin, R. (2008). Testing replication of a 5-SNP set for general cognitive ability in six population samples. Eur J Hum Genet, 16(11), 1388-95. eScholarID:1d18816 | DOI:10.1038/ejhg.2008.100
• Miyajima F, Ollier WER, Mayes AR, Jackson A-, Thacker NA, Rabbitt P-, Pendleton N, Horan M A, Payton A. (2008). Brain-derived neurotrophic factor polymorphism Val66Met influences cognitive abilities in the elderly. Genes Brain Behav, 7(4), 411-417. eScholarID:1d16825
• Miyajima F, Quinn JP, Horan M A, Pickles A, Ollier WER, Pendleton N, Payton A. (2008). Additive effect of BDNF and REST polymorphisms is associated with improved general cognitive ability. Genes Brain Behav, 7(7), 714-719. eScholarID:1d17392 | DOI:10.1111/j.1601-183X.2008.00409.x

2007

• Davidson, Y, Gibbons, L, Pritchard, A, Hardicre, J, Wren, J, Stopford, C, Julien, C, Thompson, J, Payton, A, Pickering-Brown, S, Pendleton, N, Horan, M A, Burns, AS, Purandare, N, Lendon, C, Neary, D, Snowden, JS, Mann, D. (2007). Apolipoprotein E epsilon4 allele frequency and age at onset of Alzheimer's disease. Dement Geriatr Cogn Disord, 23( 1), 60-6. eScholarID:1d16918
• Salonen, J, Uimari, P, Aalto, J, Pirskanen, M, Kaikkonen, J, Todorova, B, Hypponen, J, Korhonen, V, Asikainen, J, Devine, C, Tuomainen, T, Luedemann, J, Nauck, M, Kerner, W, Stephens, RH, New, JP, Ollier, WER, Gibson, JM, Payton, A, Horan, M A, Pendleton, N, Mahoney, W, Meyre, D, Delplanque, J, Froguel, P, Luzzatto, O, Yakir, B, Darvasi, A. (2007). Type 2 Diabetes Whole-Genome Association Study in Four Populations: The DiaGen Consortium. Am J Hum Genet, 81(2), 338-45. eScholarID:1d16155 | DOI:10.1086/520599

2006

• Davidson, YS, Gibbons, LC, Pritchard A H, Hardicre, J, Wren, J, Tian, J, Shi, J, Stopford, C, Julien, C, Thompson, J, Payton, A, Thaker, U, Hayes, A, Iwatsubo, T, Pickering-Brown, S, Pendleton, N, Horan, M A, Burns, AS, Purandare, N, Lendon, C, Neary, D, Snowden, JS, Mann, DMA. (2006). Genetic associations between cathepsin D exon 2 C->T polymorphism and Alzheimer's disease, and pathological correlations with genotype. J Neurol Neurosurg Psychiatry, 77( 4), 515-7. eScholarID:1d12925
• Davidson, YS, Gibbons, LC, Purandare N, Byrne J, Hardicre J, Wren J, Payton, A, Pendleton, N, Horan, M A, Burns, AS, Mann, DMA. (2006). Genetic risk factors and vascular dementia. Dementia Geriatr Cogn Disord, 22, 15-19. eScholarID:1d14098
• Davidson, YS, Gibbons, LC, Purandare, N, Byrne, J, Hardicre, J, Wren, J, Payton, A, Pendleton, N, Horan, M A, Burns, AS, Mann, DMA. (2006). Apolipoprotein E epsilon4 allele frequency in vascular dementia. Dement Geriatr Cogn Disord, 22( 1), 15-9. eScholarID:1d16920
• Payton A, Horan M A, Davidson YS, Gibbons LC, Ollier WER, Rabbitt P-, Worthington J, Pendleton N, Pendleton N. (2006). Influence and interactions of cathepsin D, HLA-DRB1 and APOE on cognitive abilities in an older non-demented population. Genes Brain and Behavior, 5, Suppl 1, 23-31. eScholarID:1d11375 | DOI:10.1111/j.1601-183X.2006.00191.x
• Payton A. (2006). Investigating cognitive genetics and its implications for the treatment of cognitive deficit. Genes Brain and Behavior, 5, 1, 44-53. eScholarID:1d11211
• Srinivasan R, Davidson YS, Gibbons LC, Payton A, Richardson A, Varma AR, Julien C, Stopford C, Thompson J, Horan MA, Pendleton N, Pickering-Brown SM, Neary D, Snowden JS, Mann DMA. (2006). The apolipoprotein E ε4 allele selectively increases the risk of frontotemporal lobar degeneration in males. Journal of Neurology, Neurosurgery and Psychiatry, 77, 154-158. eScholarID:1d11376
• Srinivasan, R, Davidson, Y, Gibbons, L, Payton, A, Richardson, A, Varma, A, Julien, C, Stopford, C, Thompson, J, Horan, M, Pendleton, N, Pickering-Brown, S, Neary, D, Snowden, JS, Mann, D. (2006). The apolipoprotein E epsilon4 allele selectively increases the risk of frontotemporal lobar degeneration in males. J Neurol Neurosurg Psychiatry, 77( 2), 154-8. eScholarID:1d12927

2005

• Stephens, RH, McElduff, P, Worthington, J, Ollier, WER, New, JP, Payton, A, Pendleton, N, Horan, M A, Cruickshank, (K, Gibson, JM. (2005). Single-nucleotide polymorphisms (SNPs) in the IGFBP1 gene are associated with diabetes risk and nephropathy in a cohort of type 2 diabetes mellitus patients. eScholarID:2d2022
• Ashworth J J, Smyth J Vincent, Pendleton N, Horan M A, Payton A, Worthington J, Ollier WER, Ashcroft GG. (2005). The dinucleotide (CA)repeat polymorphism of estrogen receptor beta but not the dinulclotide (TA)repeat polymorphism of estrogen receptor alpha is associated with venous ulceration. J Steroid Biochem Mol Biol, 97(3), 266-70. eScholarID:1d11193
• Payton A, Gibbons LC, Davidson YS, Ollier WER, Rabbitt P-, Worthington J, Pickles A, Pendleton N, Horan M A. (2005). Influence of serotonin transporter gene polymorphisms on cognitive decline and cognitive abilities in a nondemented elderly population. Molecular Psychiatry, 10(12), 1133-1139. eScholarID:1d11213 | DOI:10.1038/sj.mp.4001733
• Payton A, Horan M A, Davidson YS, Gibbons LC, Ollier WER, Patrick Rabbitt, Worthington Jane, Pendleton N. (2005). The influence of HLA-DRB1 on memory abilities and possible interaction with cathepsin D in an older non-demented population. Genes Brain and Behaviour, (In Press), eScholarID:1d9667
• Stevenson J, Langley K, Pay H, Payton A, Worthington J, Ollier WER, Thapar A. (2005). Attention deficit hyperactivity disorder with reading disabilities: preliminary genetic findings on the involvement of the ADRA2A gene. J Child Psychol Psychiatry, 46(10), 1081-8. eScholarID:1d11712

2004

• Lowe, N, Kirley, A, Hawi, Z, Sham, P, Wickham, H, Kratochvil, C, Smith, S, Lee, S, Levy, F, Kent, L, Middle, F, Rohde, L, Roman, T, Tahir, E, Yazgan, Y, Asherson, P, Mill, J, Thapar, A, Payton, A, Todd, R, Stephens, T, Ebstein, R, Manor, I, Barr, C, Wigg, K, Sinke, R, Buitelaar, J, Smalley, S, Nelson, S, Biederman, J, Faraone, S, Gill, M. (2004). Joint analysis of the DRD5 marker concludes association with attention-deficit/hyperactivity disorder confined to the predominantly inattentive and combined subtypes. Am J Hum Genet, 74( 2), 348-56. eScholarID:1d13136

2003

• Langley,K., Payton, A, Hamshere,M.L., Pay,H.M., Lawson,D.C., Turic,D., Ollier, WER, Worthington, J, Owen,M.J., O'Donovan,M.C., Thapar,A. (2003). No evidence of association of two 5HT transporter gene polymorphisms and attention deficit hyperactivity disorder. Psychiatric Genetics, 13, 2, 107-110. eScholarID:1d5783
• Payton, A, Holland,F., Diggle, P., Rabbitt, P-, Horan, M A, Davidson, YS, Gibbons, LC, Worthington, J, Ollier, WER, Pendleton, N. (2003). Cathepsin D exon 2 polymorphism associated with general intelligence in a healthy older population. Molecular Psychiatry, 8, 1, 14-18. eScholarID:1d5796
• Payton, A, Turic, D, Langley, K, Mills, S, Lawson, D, Van den Bree, M, Owen, M, O'Donovan, M, Ollier, WER, Worthington, J, Thapar, A. (2003). No evidence of association between HLA-DRB1 and attention deficit hyperactivity disorder. Psychiatr Genet, 13( 3), 183-5. eScholarID:1d8104
• Strickland PL, John S, Payton A, Ollier W, Deakin JFW. (2003). Do polymorphic genes influence prolactin responses to dexfenfluramine? American Journal Of Medical Genetics, 120A, 4. eScholarID:17d161
• StricklandP.L, John S, Payton A, Worthington J, Ollier WER, Deakin JFW. (2003). Do genetic polymorphisms of serotonin (5-HT) neurotransmission influence function in humans? American Journal of Medical Genetics, 120A(4), 566-567. eScholarID:17d816

2002

• Holmes,J., Payton, A, Barrett,J., Harrington,R., McGuffin,P., Owen,M., Ollier, WER, Worthington, J, Gill,M., Kirley,A., Hawi,Z., Fitzgerald,M., Asherson,P., Curran,S., Mill,J., Gould,A., Taylor,E., Kent,L., Craddock,N., Thapar,A. (2002). Association of DRD4 in children with ADHD and comorbid conduct problems. American Journal of Medical Genetics, 114, 2, 150-153. eScholarID:1d5780
• Pendleton N, Payton A, van den Boogerd EH, Holland F, Diggle P, Rabbitt PM, Horan M A, Worthington J, Ollier WER. (2002). Apolipoprotein E genotype does not predict decline in intelligence in healthy older adults. Neuroscience Letters, 324(1), eScholarID:1d2376
• Pendleton N, Payton A, van den BoogerdE.H, HollandF, DiggleP, RabbittP.M, Horan M A, Worthington J, Ollier WER. (2002). Apolipoprotein E genotype does not predict decline in intelligence in healthy older adults. Neuroscience Letters, 324, 1, 74-76. eScholarID:1d5651

2001

• Payton, A, Holmes,J., Barrett,J.H., Hever,T., Fitzpatrick,H., Trumper,A.L., Harrington,R., McGuffin,P., O'Donovan,M., Owen,M., Ollier, WER, Worthington, J, Thapar,A. (2001). Examining for association between candidate gene polymorphisms in the dopamine pathway and attention-deficit hyperactivity disorder: a family-based study. American Journal of Medical Genetics, 105, 5, 464-470. eScholarID:1d5797
• Payton, A, Holmes,J., Barrett,J.H., Sham,P., Harrington, R, McGuffin,P., Owen,M., Ollier, WER, Worthington, J, Thapar,A. (2001). Susceptibility genes for a trait measure of attention deficit hyperactivity disorder: a pilot study in a non-clinical sample of twins. Psychiatry Research, 105, 3, 273-278. eScholarID:1d5799

2000

• BrennanP, BarrettJ, FiddlerM, Thomson W, Payton A, Silman AJ. (2000). Maternal-fetal HLA incompatibility and the course of inflammatory arthritis during pregnancy. Journal of Rheumatology, 27, 12, 2843 - 2848. eScholarID:1d3630
• Holmes J, Payton, A, Barrett J H, Hever T, Fitzpatrick H, Trumper A L, Harrington, R, McGuffin P, Owen M, Ollier, WER, Worthington J, Thapar A. (2000). A family-based and case-control association study of the dopamine D4 receptor gene and dopamine transporter gene in attention deficit hyperactivity disorder. Molecular Psychiatry, 5, 523-530. eScholarID:1d23950

1999

• Harrison BJ, Thomson W, Symmons D, OllierB, Wiles N, Payton A, Barrett EM, Silman AJ. (1999). The influence of HLA-DRB1 alleles and rheumatoid factor on disease outcome in an inception cohort of patients with early inflammatory arthritis. Arthritis and Rheumatism, 42, 10, 2174 - 2183. eScholarID:1d3654
• Thomson W, Harrison BJ, OllierB, Wiles N, Payton A, BarrettJ, Symmons D, Silman AJ. (1999). Quantifying the exact role of HLA-DRB1 alleles in susceptibility to inflammatory polyarthritis: results from a large, population-based study. Arthritis and Rheumatism, 42, 4, 757 - 762. eScholarID:1d3688