Dr John McBeth
Honorary Reader
- Email: john.mcbeth@manchester.ac.uk
- Telephone: +44 (0)161 275 5788
Arthritis Research UK Epidemiology Unit
School of Translational Medicine
Musculoskeletal Research Group
The University of Manchester
Stopford Building
Oxford Road
Manchester
M13 9PT
Research
Population studies: aimed at identifying risk factors for onset and outcome of common musculoskeletal disorders.
Pain Research Group
Publications
2012
- Macfarlane, G., Beasley, M., Jones, E., Prescott, G., Docking, R., Keeley, P., McBeth, J. & Jones, G (2012). The prevalence and management of low back pain across adulthood: results from a population-based cross-sectional study (the MUSICIAN study). Pain, 153(1), 27-32. eScholarID:132958 | PMID:21978663 | DOI:10.1016/j.pain.2011.08.005
- McBeth, J. & Mulvey, M (2012). Fibromyalgia: mechanisms and potential impact of the ACR 2010 classification criteria. Nat Rev Rheumatol, 8(2), 108-16. eScholarID:155341 | PMID:22270077 | DOI:10.1038/nrrheum.2011.216
- McBeth, J., Prescott, G., Scotland, G., Lovell, K., Keeley, P., Hannaford, P., McNamee, P., Symmons, D., Woby, S., Gkazinou, C., Beasley, M. & Macfarlane, G (2012). Cognitive behavior therapy, exercise, or both for treating chronic widespread pain. Arch Intern Med, 172(1), 48-57. eScholarID:137405 | PMID:22082706 | DOI:10.1001/archinternmed.2011.555
2011
- Holliday, K. & McBeth, J (2011). Recent advances in the understanding of genetic susceptibility to chronic pain and somatic symptoms. Curr Rheumatol Rep, 13(6), 521-527. eScholarID:131461 | PMID:21877183 | DOI:10.1007/s11926-011-0208-4
- Jones, G., Nicholl, B., McBeth, J., Davies, K., Morriss, R., Dickens, C. & Macfarlane, G (2011). Road traffic accidents, but not other physically traumatic events, predict the onset of chronic widespread pain: Results from the EpiFunD study. Arthritis Care Res (Hoboken), 63(5), 696-701. eScholarID:121632 | PMID:21425478 | DOI:10.1002/acr.20417
- Nicholl, B., Holliday, K., Macfarlane, G., Thomson, W., Davies, K., O'Neill, T., Bartfai, G., Boonen, S., Casanueva, F., Finn, J., Forti, G., Giwercman, A., Huhtaniemi, I., Kula, K., Punab, M., Silman, A., Vanderschueren, D., Wu, F., McBeth, J. & EMAS_Study_Group, E (2011). HTR2A polymorphisms are associated with chronic widespread pain and the extent of musculoskeletal pain: Results from two population based cohorts. Arthritis Rheum, 63(3), 810-818. eScholarID:118627 | PMID:21305503 | DOI:10.1002/art.30185
- Tajar, A., McBeth, J., Lee, D., Macfarlane, G., Huhtaniemi, I., Finn, J., Bartfai, G., Boonen, S., Casanueva, F., Forti, G., Giwercman, A., Han, T., Kula, K., Labrie, F., Lean, M., Pendleton, N., Punab, M., Silman, A., Vanderschueren, D., O'Neill, T., Wu, F. & EMAS_Study_Group, E (2011). Elevated levels of gonadotrophins but not sex steroids are associated with musculoskeletal pain in middle-aged and older European men. Pain, 152(7), 1495-1501. eScholarID:121623 | PMID:21421286 | DOI:10.1016/j.pain.2011.01.048
- Tajar, A., O'Neill, T., Lee, D., O'Connor, D., Corona, G., Finn, J., Bartfai, G., Boonen, S., Casanueva, F., Forti, G., Giwercman, A., Han, T., Huhtaniemi, I., Kula, K., Lean, M., Pendleton, N., Punab, M., Purandare, N., Silman, A., Vanderschueren, D., Wu, F., McBeth, J. & Group, T (2011). The effect of musculoskeletal pain on sexual function in middle-aged and elderly European men: Results from the European Male Ageing Study. J Rheumatol, 38(2), 370-377. eScholarID:100722 | PMID:21159833 | DOI:10.3899/jrheum.100604
2010
- Aggarwal, V., Macfarlane, G., Farragher, T. & McBeth, J (2010). Risk factors for onset of chronic oro-facial pain - Results of the North Cheshire oro-facial pain prospective population study. Pain, 149(2), 354-359. eScholarID:78132 | PMID:20304556 | DOI:10.1016/j.pain.2010.02.040
- Halder, S., Macfarlane, G., Thompson, D., O'Brien, S., Musleh, M. & McBeth, J (2010). Predictors of persistent gastrointestinal symptoms among new presenters to primary care. Eur J Gastroenterol Hepatol, 22(3), 296-305. eScholarID:77052 | PMID:20169655 | DOI:10.1097/MEG.0b013e32832bab61
- Holliday, K., Macfarlane, G., Nicholl, B., Creed, F., Thomson, W. & McBeth, J (2010). Genetic variation in neuroendocrine genes associates with somatic symptoms in the general population: results from the EPIFUND study. J Psychosom Res, 68(5), 469-74. eScholarID:79459 | PMID:20403506 | DOI:10.1016/j.jpsychores.2010.01.024
- Holliday, K., Nicholl, B., Macfarlane, G., Thomson, W., Davies, K. & McBeth, J (2010). Genetic variation in the hypothalamic-pituitary-adrenal stress axis influences susceptibility to musculoskeletal pain: results from the EPIFUND study. Ann Rheum Dis, 69(3), 556-60. eScholarID:77801 | PMID:19723618 | DOI:10.1136/ard.2009.116137
- Lee, D., Pendleton, N., Tajar, A., O'Neill, T., O'Connor, D., Bartfai, G., Boonen, S., Casanueva, F., Finn, J., Forti, G., Giwercman, A., Han, T., Huhtaniemi, I., Kula, K., Lean, M., Punab, M., Silman, A., Vanderschueren, D., Moseley, C., Wu, F., McBeth, J. & EMAS_Study_Group, E (2010). Chronic widespread pain is associated with slower cognitive processing speed in middle-aged and older European men. Pain, 151(1), 30-36. eScholarID:87502 | PMID:20646831 | DOI:10.1016/j.pain.2010.04.024
- Macfarlane, T., McBeth, J., Jones, G., Nicholl, B. & Macfarlane, G (2010). Whether the weather influences pain? Results from the EpiFunD study in North West England. Rheumatology (Oxford), 49(8), 1513-1520. eScholarID:80565 | PMID:20430867 | DOI:10.1093/rheumatology/keq099
- McBeth, J., Nicholl, B., Cordingley, L., Davies, K. & Macfarlane, G (2010). Chronic widespread pain predicts physical inactivity: Results from the prospective EPIFUND study. Eur J Pain, 14(9), 972-979. eScholarID:79228 | PMID:20400346 | DOI:10.1016/j.ejpain.2010.03.005
- McBeth, J., Pye, S., O'Neill, T., Macfarlane, G., Tajar, A., Bartfai, G., Boonen, S., Bouillon, R., Casanueva, F., Finn, J., Forti, G., Giwercman, A., Han, T., Huhtaniemi, I., Kula, K., Lean, M., Pendleton, N., Punab, M., Silman, A., Vanderschueren, D., Wu, F. & EMAS_Study_Group, E (2010). Musculoskeletal pain is associated with very low levels of vitamin D in men: results from the European Male Ageing Study. Ann Rheum Dis, 69(8), 1448-1452. eScholarID:82915 | PMID:20498201 | DOI:10.1136/ard.2009.116053
- Nicholl, B., Holliday, K., Macfarlane, G., Thomson, W., Davies, K., O'Neill, T., Bartfai, G., Boonen, S., Casanueva, F., Finn, J., Forti, G., Giwercman, A., Huhtaniemi, I., Kula, K., Punab, M., Silman, A., Vanderschueren, D., Wu, F., McBeth, J. & EMAS_Study_Group, E (2010). No evidence for a role of the catechol-O-methyltransferase pain sensitivity haplotypes in chronic widespread pain. Ann.Rheum.Dis, 69(11), 2009-2012. eScholarID:85007 | DOI:10.1136/ard.2009.126086
2009
- Davies KA, Silman AJ, Macfarlane GJ, Nicholl BI, Dickens C, Morriss R, Ray DW, McBeth J. (2009). The association between neighbourhood socio-economic status and the onset of chronic widespread pain: Results from the EPIFUND study. Eur J Pain, 13(6), 635-640. eScholarID:1d18229 | DOI:10.1016/j.ejpain.2008.07.003
- Davies, K., Macfarlane, G., McBeth, J., Morriss, R. & Dickens, C (2009). Insecure attachment style is associated with chronic widespread pain. Pain, 143(3), 200-5. eScholarID:77802 | PMID:19345016 | DOI:10.1016/j.pain.2009.02.013
- Holliday, K., Nicholl, B., Macfarlane, G., Thomson, W., Davies, K. & McBeth, J (2009). Do genetic predictors of pain sensitivity associate with persistent widespread pain? Mol Pain, 5, 56. eScholarID:78106 | PMID:19775452 | DOI:10.1186/1744-8069-5-56
- Jones EA, McBeth J, Nicholl BI, Morriss RK, Dickens C, Jones GT, Macfarlane GJ. (2009). What characterizes persons who do not report musculoskeletal pain? Results from a 4-year population-based longitudinal study (The Epifund Study). J Rheumatol, 48(10), 1323-1327. eScholarID:1d19077 | DOI:10.3899/jrheum.080541
- McBeth, J., Symmons, D., Silman, A., Allison, T., Webb, R., Brammah, T., Macfarlane, G. & EMAS_Study_Group, E (2009). Musculoskeletal pain is associated with a long-term increased risk of cancer and cardiovascular-related mortality. Rheumatology (Oxford), 48(1), 74-7. eScholarID:77803 | PMID:19056799 | DOI:10.1093/rheumatology/ken424
- McBeth, J., Tajar, A., O'Neill, T., Macfarlane, G., Pye, S., Bartfai, G., Boonen, S., Bouillon, R., Casanueva, F., Finn, J., Forti, G., Giwercman, A., Han, T., Huhtaniemi, I., Kula, K., Lean, M., Pendleton, N., Punab, M., Silman, A., Vanderschueren, D. & Wu, F (2009). Perturbed insulin-like growth factor-1 (IGF-1) and IGF binding protein-3 are not associated with chronic widespread pain in men: results from the European Male Ageing Study. J Rheumatol, 36(11), 2523-30. eScholarID:76164 | PMID:19833751 | DOI:10.3899/jrheum.090113
- Nicholl BI, Macfarlane GJ, Davies KA, Morriss R, Dickens C, McBeth J. (2009). Premorbid psychosocial factors are associated with poor health-related quality of life in subjects with new onset of chronic widespread pain - Results from the EPIFUND study. Pain, 141 (1-2), 119-126. eScholarID:1d18233 | DOI:10.1016/j.pain.2008.10.022
2008
- Aggarwal VR, McBeth J, Zakrzewska J, Macfarlane G. (2008). Unexplained orofacial pain - is an early diagnosis possible? Br Dent J, 205 (3), E6; discussion 140-1. eScholarID:1d18146 | DOI:10.1038/sj.bdj.2008.585
- Aggarwal VR, McBeth J, Zakrzewska JM, Lunt M, Macfarlane GJ. (2008). Are reports of mechanical dysfunction in chronic oro-facial pain related to somatisation? A population based study. Eur J Pain, 12 (4), 501-7. eScholarID:1d16548 | DOI:10.1016/j.ejpain.2007.08.002
- Davies KA, Macfarlane G, Nicholl BI, Dickens C, Morriss R, Ray D, McBeth J. (2008). Restorative sleep predicts the resolution of chronic widespread pain: results from the EPIFUND study. Rheumatology (Oxford), 47 (12), 1809-13. eScholarID:1d18231 | DOI:10.1093/rheumatology/ken389
- Griffith, L., Wells, R., Shannon, H., Walter, S., Cole, D., Hogg-Johnson, S. & MAPLE_Collaborative_Group, M (2008). Developing common metrics of mechanical exposures across aetiological studies of low back pain in working populations for use in meta-analysis. Occup Environ Med, 65(7), 467-81. eScholarID:66658 | PMID:17991699 | DOI:10.1136/oem.2007.034801
- Limer KL, Nicholl BI, Thomson W, McBeth J. (2008). Exploring the genetic susceptibility of chronic widespread pain: the tender points in genetic association studies. Rheumatology (Oxford), 47( 5), eScholarID:1d17515
- Nicholl BI, Halder SL, G Macfarlane, Thompson DG, O'Brien SJ, M Musleh, McBeth J. (2008). Psychosocial risk markers for new onset irritable bowel syndrome -results of a large prospective population-based study. Pain, 137(1), 147-55. eScholarID:1d28279
2007
- Aggarwal VR, McBeth J, Lunt M, Zakrzewska J, Macfarlane G. (2007). Development and validation of classification criteria for idiopathic orofacial pain for use in population-based studies. J Orofac Pain, 21( 3), 203-15. eScholarID:1d16179
- Griffith, L., Hogg-Johnson, S., Cole, D., Krause, N., Hayden, J., Burdorf, A., Leclerc, A., Coggon, D., Bongers, P., Walter, S., Shannon, H. & MAPLE_Collaborative_Group, M (2007). Low-back pain definitions in occupational studies were categorized for a meta-analysis using Delphi consensus methods. J Clin Epidemiol, 60(6), 625-33. eScholarID:66659 | PMID:17493522 | DOI:10.1016/j.jclinepi.2006.09.005
- Gupta A, McBeth J, Macfarlane G, MorrissR.K, Dickens C, Ray DW, ChiuY.H, Silman AJ. (2007). Pressure pain thresholds and tender point counts as predictors of new chronic widespread pain in somatising subjects. Annals of the Rheumatic Diseases, 66 (4), 517-521. eScholarID:1d14259
- Gupta A, Silman AJ, Ray DW, Morriss R, Dickens C, Macfarlane G, ChiuY.H, Nicholl BI, McBeth J. (2007). The role of psychosocial factors in predicting the onset of chronic widespread pain: results from a prospective population-based study. Rheumatology, 46 (4), 666-671. eScholarID:1d14247
- Jones GT, Harkness EF, Nahit ES, McBeth J, Silman AJ, Macfarlane G. (2007). Predicting the onset of knee pain: results from a two year prospective study of new workers. Ann Rheum Dis, 66 (3), 400-406. eScholarID:1d14368
- Macfarlane G, Jones G, Knekt P, Aromaa A, McBeth J, Mikkelsson M, Heliovaara M. (2007). Is the report of widespread body pain associated with long-term increased mortality? Data from the Mini-Finland Health Survey. Rheumatology (Oxford), 46( 5), 805-7. eScholarID:1d15737
- McBeth J, Silman AJ, Gupta A, Chiu Y, Ray DW, Morriss R, Dickens C, King YE, Macfarlane G. (2007). Moderation of psychosocial risk factors through dysfunction of the hypothalamic-pituitary-adrenal stress axis in the onset of chronic widespread musculoskeletal pain: findings of a population-based prospective cohort study. Arthritis Rheum, 56( 1), 360-71. eScholarID:1d15660 | DOI:10.1002/art.22336
2006
- Aggarwal VR, McBeth J, Zakrzewska J, Lunt M, Macfarlane G. (2006). The epidemiology of chronic syndromes that are frequently unexplained: do they have common associated factors? Int J Epidemiol, 35( 2), 468-76. eScholarID:1d14365 | DOI:10.1093/ije/dyi265
2005
- Chiu Y, Silman AJ, Macfarlane G, Ray DW, Gupta A, Dickens C, Morriss R, McBeth J. (2005). Poor sleep and depression are independently associated with a reduced pain threshold. Results of a population based study. Pain, 115( 3), 316-21. eScholarID:1d11806
- Harkness EF, Macfarlane G, Silman AJ, McBeth J. (2005). Is musculoskeletal pain more common now than 40 years ago?: Two population-based cross-sectional studies. Rheumatology (Oxford), 44( 7), 890-5. eScholarID:1d11803 | DOI:10.1093/rheumatology/keh599
- Kapur NN, Hunt IM, Lunt M, McBeth J, Creed FH, Macfarlane G. (2005). Primary care consultation predictors in men and women: a cohort study. Br J Gen Pract, 55( 511), eScholarID:1d10647
- McBeth J, Chiu Y, Silman AJ, Ray DW, Morriss R, Dickens C, Gupta A, Macfarlane G. (2005). Hypothalamic-pituitary-adrenal stress axis function and the relationship with chronic widespread pain and its antecedents. Arthritis Res Ther, 7( 5), R992-R1000. eScholarID:1d11801 | DOI:10.1186/ar1772
2004
- Harkness EF, Macfarlane G, Nahit E, Silman AJ, McBeth J. (2004). Mechanical injury and psychosocial factors in the work place predict the onset of widespread body pain: a two-year prospective study among cohorts of newly employed workers. Arthritis Rheum, 50( 5), 1655-64. eScholarID:1d8100 | DOI:10.1002/art.20258
- Kapur NN, Hunt IM, Lunt M, McBeth J, Creed FH, Macfarlane G. (2004). Psychosocial and illness related predictors of consultation rates in primary care--a cohort study. Psychol Med, 34( 4), eScholarID:1d8102
- Kapur NN, Hunt IM, Macfarlane G, McBeth J, Creed FH. (2004). Childhood experience and health care use in adulthood: nested case--control study. Br J Psychiatry, 185, eScholarID:1d9342 | DOI:10.1192/bjp.185.2.134
- Robinson KL, McBeth J, Macfarlane G. (2004). Psychological distress and premature mortality in the general population: a prospective study. Ann Epidemiol, Aug;14(7), 467-72. eScholarID:1d26175
- McBeth J, Gupta A, Silman AJ, Macfarlane G. (2004). Hypothalmic-pituitary-adrenal stress axis function - the relationship with chronic widespread pain and its antecedents: a population-based study. Rheumatology, 43 (suppl 2), ii7. eScholarID:17d598
- McBeth J, Silman AJ, Macfarlane G. (2004). Is musculoskeletal pain more common now than 40 years ago? Results from two population-based cross-sectional studies. Rheumatology, 43 (suppl 2), ii7. eScholarID:17d317
2003
- Harkness EF, Macfarlane G, NahitE.S, Silman AJ, McBeth J. (2003). Risk factors for new-onset low back pain amongst cohorts of newly employed workers. Rheumatology, 42, 8, 959-968. eScholarID:1d5517
- Harkness EF, MacfarlaneG.J, NahitE.S, Silman AJ, McBeth J. (2003). Mechanical and psychosocial factors predict new onset shoulder pain: a prospective cohort study of newly employed workers. OEM, 60 (11), 850-857. eScholarID:1d5820
- McBeth J, Harkness EF, Silman AJ, Macfarlane G. (2003). The role of workplace low-level mechanical trauma, posture and environment in the onset of chronic widespread pain. Rheumatology, 42(12), 1486-94. eScholarID:1d5933
- McBeth J, Silman AJ, Macfarlane G. (2003). Association of widespread body pain with an increased risk of cancer and reduced cancer survival: a prospective, population-based study. Arthritis and Rheumatism, 48, 6, 1686-1692. eScholarID:1d5927 | DOI:10.1002/art.10973
- Harkness EF, Nahit E, Macfarlane G, Silman AJ, McBeth J, Dunn G. (2003). Generalised estimating equations and low back pain. Occupational and Environmental Medicine, 60, 5, 378-380. eScholarID:17d249
2002
- Halder SL, McBeth J, Silman AJ, Thompson DG, Macfarlane G. (2002). Psychosocial risk factors for the onset of abdominal pain: results from a large prospective population-based study. International Journal of Epidemiology, 31(6), 1219-25. eScholarID:1d2068 | DOI:10.1093/ije/31.6.1219
- McBeth J, Macfarlane G, Silman AJ. (2002). Does chronic pain predict future psychological distress? Pain, 96, 3, 239 - 245. eScholarID:1d3677 | DOI:10.1016/S0304-3959(01)00452-3
2001
- Macfarlane G, McBeth J, Silman AJ. (2001). Widespread body pain and mortality: prospective population based study. BMJ, 323, 7314, 662-665. eScholarID:1d5526 | DOI:10.1136/bmj.323.7314.662
- McBeth J, Macfarlane G, HuntI.M, Silman AJ. (2001). Risk factors for persistent chronic widespread pain: a community-based study. Rheumatology, 40, 1, 95 - 101. eScholarID:1d3673
- McBeth J, MacfarlaneG.J, BenjaminS, Silman AJ. (2001). Features of somatization predict the onset of chronic widespread pain: results of a large population-based study. Arthritis and Rheumatism, 44, 4, 940-946. eScholarID:1d5929
- McBeth J, MorrisS, BenjaminS, Silman AJ, Macfarlane G. (2001). Associations between adverse events in childhood and chronic widespread pain in adulthood: are they explained by differential recall? Journal of Rheumatology, 28, 10, 2305 - 2309. eScholarID:1d3675
- McBeth J, Silman AJ. (2001). The role of psychiatric disorders in fibromyalgia. Curr. Rheumatol. Rep, 3, 2, 157-164. eScholarID:1d5931
- Halder SL, McBeth J, Roland M, Thompson DG, Macfarlane G. (2001). Risk factors for the onset of functional abdominal pain: A prospective population based study. Gastroenterology, 120, A230. eScholarID:17d189
2000
- BenjaminS, MorrisS, McBeth J, Macfarlane G, Silman AJ. (2000). The association between chronic widespread pain and mental disorder: a population-based study. Arthritis and Rheumatism, 43, 3, 561 - 567. eScholarID:1d3628
1999
- McBeth J, Macfarlane G, BenjaminS, MorrisS, Silman AJ. (1999). The association between tender points, psychological distress, and adverse childhood experiences: a community-based study. Arthritis and Rheumatism, 42, 7, 1397 - 1404. eScholarID:1d3671
- Holliday, K., Nicholl, B., Macfarlane, G., Thomson, W., Davies, K. & McBeth, J Do genetic predictors of pain sensitivity associate with persistent widespread pain? Mol Pain, 5, 56. eScholarID:77800 | PMID:19775452 | DOI:10.1186/1744-8069-5-56