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School of Medicine

Dr Andrea Murray 

Photograph of Andrea Murray

Arthritis Research UK Career Development Research Fellow

C214, Clinical Sciences Building, Salford Royal Hospital, Salford, M6 8HD

 

 

Role

I am a Research Fellow; my area of interest is light-tissue interaction. My work is based at Salford Royal Hospital and in the Photon Science Institute (School of Physics and Astronomy).

 

Memberships of Committees and Professional Bodies

  • Institute of Physics (1998)
  • British Microcirculation Society (2003)
  • UK Optical Coherence Tomography (OCT) Interest Group (2005)
  • British Society for Rheumatology (2006)
  • British Medical Laser Association (2007)

Research

I began a 4 yr Stepping Stone Award in September 2005; the title of my project is ‘Optical techniques for imaging structure and blood flow in microvascular disease’. The project involves developing and implementing existing and new, non-invasive, light-based imaging modalities (nailfold capillaroscopy and Optical Doppler Tomography [ODT]) for measuring cutaneous perfusion for the purpose of monitoring disease progression and treatment response. These techniques will be used, initially, on patients with systemic sclerosis, psoriasis and diabetes. In addition novel treatments for two aspects of the systemic sclerosis disease (telangiectases and digital ischaemia) will be piloted. This is a multi-disciplinary project, involving a significant amount of collaboration with other groups within the university and with industry. Other ongoing studies with which I am involved include light-tissue interaction modelling and tissue phantom studies to clarify the mechanism of our novel dual wavelength Laser Doppler Imaging (LDI) technique and LDI treatment response studies in patients with psoriasis.

 

In January 2011 I began an Arthritis Research UK Fellowship  entitled 'Shedding light on the cause of systemic sclerosis: Can non-invasive imaging techniques elucidate pathogenesis and measure disease?' and will involve development of optical coherence tomography, nailfold capillaroscopy and hyperspectral imaging.

 

Qualifications

  • 1998 - MPhys (Physics)
  • 2001 - PhD (Physics)
 

Publications

2012

  • Andrea Murray, Andy Vail, Tonia Moore, Joanne Manning, Chris Taylor, Ariane Herrick. (2012). The influence of measurement location on reliability of quantitative nailfold videocapillaroscopy in patients with systemic sclerosis. Rheumatology, eScholarID:144642

2011

  • A Herrick, T Moore, A Murray, N Whidby, J Manning, M Bhushan, A Vail. (2011). Nailfold capillary abnormalities are associated with anticentromere antibody and severity of digital ischaemia. Rheumatology, 49, 1776-1782. eScholarID:133614 | DOI:10.1093/rheumatology/keq139
  • A Murray, K Feng, T Moore, P Allen, C Taylor, A Herrick. (2011). Preliminary clinical evaluation of semi-automated nailfold capillaroscopy in the assessment of patients with Raynaud’s phenomenon. Microcirculation, 18, 440-447. eScholarID:133617 | DOI:10.1111/j.1549-8719.2011.00104.x
  • P Shah, A Murray, T Moore, A Herrick. (2011). Pilot study of effects of iloprost on microvascular structure as a assessed by nailfold videocapillaroscopy. J Rheumatol, 38, 2079-2080. eScholarID:133618 | DOI:10.3899/jrheum.110067
  • A Murray, T Moore, A Herrick. Clinical images: Winners of the 2010 American College of Rheumatology Annual Image Competition. Arthritis and Rheumatism 2011; 63: 865–6. eScholarID:133616

2010

  • H Sadik, T Moore, A Vail, A Murray, M Anderson, A Blann, A Herrick. (2010). Lack of effect of 8 weeks’ Atorvastatin on microvascular endothelial function in patients with systemic sclerosis. Rheumatology, 49, 990-996. eScholarID:133612 | DOI:10.1093/rheumatology/keq003
  • L Mercer, T Moore, A Murray, H Chinoy, R Cooper, A Herrick. (2010). Quantitative nailfold video capillaroscopy in patients with idiopathic inflammatory myopathy. Rheumatology, 49, 1699-1705. eScholarID:133613 | DOI:10.1093/rheumatology/keq051
  • T Moore, C Roberts, A Murray, I Helbling, A Herrick. (2010). Reliability of dermoscopy in the assessment of patients with Raynaud’s phenomenon. Rheumatology, 49, 542-547. eScholarID:133611 | DOI:10.1093/rheumatology/kep408
  • A Murray, T Moore, A Herrick. Clinical images: Scleroderma related telangiectases. Arthritis and Rheumatism 2010; 63: 572. eScholarID:133615

2009

  • Moore TL, Vij S, Murray AK, Bhushan M, Griffiths CE, Herrick AL. (2009). Pilot study of dual-wavelength (532 and 633 nm) laser Doppler imaging and infrared thermography of morphoea. Br J Dermatol, 160, (4), 864-7-867. eScholarID:1d18238 | DOI:10.1111/j.1365-2133.2008.08933.x
  • Murray AK, Moore TL, Griffiths CEM, Herrick AL. (2009). An investigation into the blood-flow characteristics of telangiectatic skin lesions in systemic sclerosis using dual-wavelength laser Doppler imaging. Clin Exp Dermatol, 34, 618-620. eScholarID:1d19238 | DOI:10.1111/j.1365-2230.2008.03170.x
  • Murray AK, Moore TL, Manning JB, Taylor C, Griffiths CEM, Herrick AL. (2009). Non-invasive imaging techniques in the assessment of scleroderma-spectrum disorders. Arthritis Care and research, 61, 1103-11-1011. eScholarID:1d21839 | DOI:10.1002/art.24645

2008

  • Murray AK, Moore T, King T, Herrick AL. (2008). Vasodilator iontophoresis a possible new therapy for digital ischaemia in systemic sclerosis? Rheumatology (Oxford), 47 (1), 76-79. eScholarID:1d16847 | DOI:10.1093/rheumatology/kem314

2006

  • Murray AK, Moore TL, King TA, Herrick AL. (2006). Abnormal microvascular response is localised to the digits in patients with systemic sclerosis. Arthritis and Rheumatism, 54, 1952-1960. eScholarID:1d12903 | DOI:10.1002/art.21911

2005

  • Murray AK, Attrill D, Dickinson MR. (2005). Qualitative assessment of surface topographyof XeCl laser etched NiCr alloy. Dental Materials, 21, eScholarID:1d12873
  • Murray AK, Attrill D, Dickinson MR. (2005). The effects of XeCl laser etching of Ni-Cr alloy on bond strengths to composite resin: a comparison with sandblasting procedures. Dental Materials, 21, 538-544. eScholarID:1d12975
  • Murray AK, Herrick AL, Gorodkin RE, Moore TL, King T. (2005). Possible therapeutic use of vasodilator iontophoresis. Microvascular Research, 69, 89-94. eScholarID:1d11092 | DOI:10.1016/j.mvr.2005.01.005
  • Murray AK, Herrick AL, Moore TL, King TA, Griffiths CEM. (2005). Dual wavelength (532 and 633nm) laser Doppler imaging of plaque psoriasis. British Journal of Dermatology, 152, 1182-1186. eScholarID:1d12853 | DOI:10.1111/j.1365-2133.2005.06479.x

2004

  • Murray AK, Dickinson MR. (2004). High speed photography of plasma during excimer laser-tissue interaction. Physics in Medicine and Biology, 49, 3325-3340. eScholarID:1d12973
  • Murray AK, Dickinson MR. (2004). Tissue ablation-rate measurements with a long-pulsed, fibre-deliverable 308 nm excimer laser. Lasers in Medical Science, 19, 127-138. eScholarID:1d12971
  • Murray AK, Herrick AL, King T. (2004). Laser Doppler imaging: a developing technique for application in the rheumatic diseases. Rheumatology, 43, 1210-1218. eScholarID:1d12851
  • Murray AK, R E Gorodkin, T L Moore, R J Gush, Herrick AL, T A King. (2004). Comparison of red and green laser Doppler imaging of blood flow. Lasers in Medicine and Surgery, 35, 191-200. eScholarID:1d9635 | DOI:10.1002/lsm.20085

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