Dr Lloyd Gregory
Translational Imaging Unit Manager
- Email: lloyd.gregory@manchester.ac.uk
- Telephone: +44 (0)161 206 5832/ 906 7508
- Alternative Telephone: 0161 275 5761 (Secretary)
- Fax: 0161 275 5784
Role
Translational Imaging Unit Research Manager
Translational Imaging Unit, 3T MRI Facility, Hope Hospital, Stott Lane, Salford, M6 8WH
Research
Lloyd's research interests focus on understanding the complex interactions of sensory, affective and cognitive components of the visceral pain neuromatrix and how they can be modulated by psychological and pharmacological means. This is of particular clinical relevance to understanding the pathophysiological mechanisms that underpin functional gastrointestinal disorders such as irritable bowel syndrome (IBS) and non-cardiac chest pain. Much of Lloyd's research involves the use of functional magnetic resonance imaging techniques. However, his current role now enables him to forge new research collaborations that utilise magnetic resonance imaging in order to translate clinical questions into imaging science.
Lloyd maintains research collaborations with Professor Simon Baron-Cohen (Cambridge University), Professor Steve Williams (Insitute of Psychiatry, London), Professor David Thompson (University of Manchester) and Professor Jan Tack at the University of Leuven, Belgium.
Qualifications
BSc(Hons) Neurosciences - Upper Second Class - University of Central Lancashire, Preston
1999 PhD in Psychology and Neuroimaging - Departments of Psychology and Neurology, Instititue of Psychiatry, King's College, London
Publications
2009
- Kleyn, CE, McKie, S, Ross, A, Montaldi, D, Gregory, LJ, Elliott, R, Isaacs, C, Anderson, I, Richards, HL, Deakin, JFW, Fortune, D, Griffiths, CEM. (2009). Diminished neural and cognitive responses to facial expressions of disgust in patients with psoriasis: a fMRI study. J Invest Dermatol, 129 (11), 2613-2619. eScholarID:1d21110 | DOI:10.1038/jid.2009.152
- Paine PP, Worthen SF, Gregory LJ, Thompson DG, Aziz Q. (2009). Personality differences affect brainstem autonomic responses to visceral pain. Neurogastroenterol Motil, eScholarID:1d19921 | DOI:10.1111/j.1365-2982.2009.01348.x
- Richardson PC, Williams SR, Hepenstall S, Gregory LJ, McKie S, Corrigan F. (2009). A Single-Case fMRI Study: EMDR Treatment of a Patient With Posttraumatic Stress Disorder. Journal of EMDR Practice and Research, 3, eScholarID:1d19536
2008
- Paine P, Hamdy S, X Chitnis, Gregory LJ, V Giampitro, M Brammer, S Williams, Aziz Q. (2008). Modulation of activity in swallowing motor cortex following esophageal acidification: a functional magnetic resonance imaging study. Dysphagia, 23(2), eScholarID:1d28277
2005
- L Yaguez, Coen SJ, Gregory LJ, E Amaro Jr, C Altman, MJ Brammer, ET Bullmore, SC Williams, Aziz Q. (2005). Brain response to visceral aversive conditioning: a functional magnetic resonance imaging study. Gastroenterology, 128(7), 1819-29. eScholarID:1d11266 | DOI:10.1053/j.gastro.2005.02.068
2003
- Gregory LJ, Haga KK, Hicks CA, Ward MA, Beech JS, Bath PW, Williams SCR, O'Neill MJ. (2003). The neuronal nitric oxide synthase inhibitor, TRIM, as a neuroprotective agent: effects in models of cerebral ischaemia using histological and magnetic resonance imaging techniques. Brain Research, 993, 42-53. eScholarID:1d9818
- Gregory LJ, Yaguez L, Williams SCR, Altmann C, Coen SJ, Ng VWK, Brammer MJ, Thompson DG, Aziz Q. (2003). Cognitive Modulation of the Cerebral Processing of Human Oesophageal Sensation using Functional Magnetic Resonance Imaging. GUT, 52, 1671-1677. eScholarID:1d6568 | DOI:10.1136/gut.52.12.1671
- Phillips ML, Gregory, LJ, Cullen S, Coen, SJ, Ng V`, Andrew C, Giampietro V, Bullmore E, Zelaya F, Amaro E, Thompson, DG, Hobson, AR, Williams SCR, Brammer M, Aziz, Q. (2003). The Effect of Negative Emotional Context on Neural and Behavioural Responses to Oesophageal Stimulation. Brain, 126 (pt3), eScholarID:1d6564 | DOI:10.1093/brain/awg065
2002
- Nunn J A, Gregory, LJ, Brammer, MJ, Williams, SC, Parslow DM, Morgan MJ, Morris, RG, Bullmore, ET, Baron-Cohen, S, Gray, JA. (2002). Functional magnetic resonance imaging of synesthesia: activation of V4/V8 by spoken words. Nature Neuroscience, 5(4), 371-5. eScholarID:1d2073 | DOI:10.1038/nn818
2001
- Gregory LJ, O'Neill MJ, Nunn JA, Gray JA, Williams SCR. (2001). Diffusion weighted MRI detects early neuropathology following four vessel occlusion. J. MRI, 14(3), 207-14. eScholarID:1d2072
1998
- Mayes, A, Mayes, AR, Gooding, P, Hunkin, N, Nunn, J, Gregory, LJ, Brammer, M, Bullmore, E, Giampietro, V, Van Eijk, R, Nicholas, A, Williams, S. (1998). Storage of verbal associations is sufficient to activate the left medial temporal lobe. Behav Neurol, 11( 3), eScholarID:1d29791