Dr Peter Arkwright FRCPCH, D Phil (Oxon)

2010

• Arkwright, P., Luchetti, F., Tour, J., Roberts, C., Ayub, R., Morales, A., Rodríguez, J., Gilmore, A., Canonico, B., Papa, S. & Esposti, M (2010). Fas stimulation of T lymphocytes promotes rapid intercellular exchange of death signals via membrane nanotubes. Cell Res, 20(1), 72-88. eScholarID:96164 | PMID:19770844 | DOI:10.1038/cr.2009.112
• Avery, D., Deenick, E., Ma, C., Suryani, S., Simpson, N., Chew, G., Chan, T., Palendira, U., Bustamante, J., Boisson-Dupuis, S., Choo, S., Bleasel, K., Peake, J., King, C., French, M., Engelhard, D., Al-Hajjar, S., Al-Muhsen, S., Magdorf, K., Roesler, J., Arkwright, P., Hissaria, P., Riminton, D., Wong, M., Brink, R., Fulcher, D., Casanova, J., Cook, M. & Tangye, S (2010). B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans. J Exp Med, 207(1), 155-71. eScholarID:96167 | PMID:20048285 | DOI:10.1084/jem.20091706
• Booth, et al (2010). X-linked lymphoproliferative disease due to SAP/SH2D1A deficiency: a multicenter study on the manifestations, management, and outcome of the disease. Blood, Epub ahead of print, eScholarID:96174 | PMID:20926771 | DOI:10.1182/blood-2010-06-284935
• Capps, J., Sharma, V. & Arkwright, P (2010). Prevalence, outcome and pre-hospital management of anaphylaxis by first aiders and paramedical ambulance staff in Manchester, UK. Resuscitation, 81(6), 653-7. eScholarID:96170 | PMID:20189286 | DOI:10.1016/j.resuscitation.2010.01.021
• Hislop, A., Palendira, U., Leese, A., Arkwright, P., Rohrlich, P., Tangye, S., Gaspar, H., Lankester, A., Moretta, A. & Rickinson, A (2010). Impaired Epstein-Barr virus-specific CD8+ T-cell function in X-linked lymphoproliferative disease is restricted to SLAM family-positive B-cell targets. Blood, 116(17), 3249-57. eScholarID:96171 | PMID:20644117 | DOI:10.1182/blood-2009-09-238832
• Ng, W., von Delwig, A., Carmichael, A., Arkwright, P., Abinun, M., Cant, A., Jolles, S. & Lilic, D (2010). Impaired T(H)17 responses in patients with chronic mucocutaneous candidiasis with and without autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy. J Allergy Clin Immunol, 126(5), 1006-15, 1015.e1-4. eScholarID:96175 | PMID:20934207 | DOI:10.1016/j.jaci.2010.08.027
• Puel, A., Döffinger, R., Natividad, A., Chrabieh, M., Barcenas-Morales, G., Picard, C., Cobat, A., Ouachée-Chardin, M., Toulon, A., Bustamante, J., Al-Muhsen, S., Al-Owain, M., Arkwright, P., Costigan, C., McConnell, V., Cant, A., Abinun, M., Polak, M., Bougnères, P., Kumararatne, D., Marodi, L., Nahum, A., Roifman, C., Blanche, S., Fischer, A., Bodemer, C., Abel, L., Lilic, D. & Casanova, J (2010). Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I. J Exp Med, 207(2), 291-7. eScholarID:96166 | PMID:20123958 | DOI:10.1084/jem.20091983
• Santer, D., Hall, B., George, T., Tangsombatvisit, S., Liu, C., Arkwright, P. & Elkon, K (2010). C1q deficiency leads to the defective suppression of IFN-alpha in response to nucleoprotein containing immune complexes. J Immunol, 185(8), 4738-49. eScholarID:96173 | PMID:20844193 | DOI:10.4049/jimmunol.1001731

2009

• Hong, M, Ryan, K, Arkwright, PD, Gennery, A, Costigan, C, Dominguez, M, Denning, DW, McConnell, V, Cant, A, Abinun, M, Spickett, G, Swan, D, Gillespie, C, Young, D, Lilic, D. (2009). Pattern recognition receptor expression is not impaired in patients with chronic mucocutanous candidiasis with or without autoimmune polyendocrinopathy candidiasis ectodermal dystrophy. Clin Exp Immunol, Epub ahead of print, eScholarID:1d18795 | DOI:10.1111/j.1365-2249.2009.03873.x

2008

• B Nedjai, G A Hitman, N Yousaf, Y Chernajovsky, S Stjernberg-Salmela, T Pettersson, A Ranki, P N Hawkins, Arkwright, PD, M F McDermott, M D Turner. (2008). Abnormal tumor necrosis factor receptor I cell surface expression and NF-kappaB activation in tumor necrosis factor receptor-associated periodic syndrome. Arthritis and Rheumatism, 58(1), 273-83. eScholarID:1d17030 | DOI:10.1002/art.23123

2007

• Arkwright PD, Mario Abinun, Andrew J Cant. (2007). Mevalonic aciduria cured by bone marrow transplantation. New England Journal of Medicine, 357, eScholarID:1d17028

2006

• Alachkar H, Taubenheim N, Haeney MR, Durandy A, Arkwright PD. (2006). Memory switched B-cell percentage and not serum immunoglobulin concentration is associated with clinical complications in children and adults with specific antibody deficiency and common variable immunodeficiency. Clinical Immunology, 120(3), 310-8. eScholarID:1d13412 | DOI:doi:10.1016/j.clim.2006.05.003
• Chapgier A, Boisson-Dupuis S, Jouranguy E, Vogt G, Feinberg J, Prochnicka-Chalufour A, Casouge A, Yang K, Soudais C, Fieschi C, de Filipe Santos O, Bustamante J, Picardi C, de Beaucoudrey L, Emiles JF, Arkwright, PD, Schreiber RD, Rolinck-Werninghaus C, Rosen-Wolff A, Magdorfe K, Roesler J, Casanova JL. (2006). Novel STAT1 alleles in otherwise healthy patients with mycobacterial disease. PLOS Genetics, 2(8), e131. eScholarID:1d13812 | DOI:DOI: 10.1371/journal.pgen.0020131
• Chapgier A, Wynn RF, Emmanuelle J, Orchidée F-S, Shenying Z, Jacqueline F, Kay H, Jean-Laurent C, Arkwright PD. (2006). Human complete Stat-1 deficiency is associated with defective type I and II interferon production in vitro but immunity to some low virulence viruses in vivo. Journal of Immunology, 176, 5078-5083. eScholarID:1d12687
• Moore K, David TJ, Murray CS, Fran Child, Arkwright PD. (2006). Relative effect of childhood eczema versus asthma on parental sleep, depression and anxiety scores: a prospective comparative study. British Journal of Dermatology, 154(3), 514-8. eScholarID:1d12684
• Theilgaard-Monch K, Jacobson LC, Nielsen MJ, Rasmussen T, Udby L, Gharib M, Arkwright, PD, Gombart AF, Calafat J, Moestrup SK, Porse BT, Borregaard N. (2006). Haptoglobin is synthesized during granulocytic differentiation, stored in specific granules, and released by neutrophils in response to activation. Blood, 108(1), 353-61. eScholarID:1d13410 | DOI:DOI 10.1182/blood-2005-09-3890
• Uddin S, Borrow R, Haeney MR, Moran A, Warrington R, Balmer P, Arkwright PD. (2006). Total and serotype-specific pneumococcal antibody titres in children and with normal immunity and immunodeficiency diseases. Vaccine, 24(27-28), 5637-44. eScholarID:1d13411 | DOI:doi:10.1016/j.vaccine.2006.03.088

2005

• Arkwright PD, Fujisawa C, Tanaka A, Matsuda H. (2005). Mycobacterium vaccae reduces scratching behavior but not the rash in NC mice with eczema: A randomized, blinded, placebo-controlled trial. Journal Of Investigative Dermatology, 124, 140-143. eScholarID:1d26610
• Ryan K.R, Lawson C, Arkwright PD, Isaacs J.D, Lilic D. (2005). CD4+CD25+ T regulatory cells in patients with Autoimmune PolyEndocrinopathy Candidiasis Ectodermal Dystrophy (APECED) syndrome. Journal Of Allergy And Clinical Immunology, 116, 1158-9. eScholarID:1d26616
• Wynn RF, Arkwright PD, Haque T, Gharib M.I, Wilkie G, Morton-Jones M, Crawford D.H. (2005). Treatment of Epstein-Barr-virus-associated primary CNS B cell lymphoma with allogeneic T-cell immunotherapy and stem-cell transplantation. The Lancet Oncology, 6 (5), 344-346. eScholarID:1d26614

2004

• Holzelova E, Vonarbourg C, Stolzenberg M-C, Arkwright, PD, Selz F, Prieur A-M, Blanche S, Bartunkova J, Vilmer E, Fischer A, Le Deist F, Rieux-Laucat F. (2004). Autoimmune lymphoproliferative syndrome (ALPS-III) caused by somatic mutations of TNFRSF6 (fas). New England Journal of Medicine, 351, 1409-1418. eScholarID:1d10161
• Sharifi R, Sinclair JC, Gilmour KC, Arkwright PD, Kinnon C, Thrasher AJ, Gaspar HB. (2004). SAP mediates specific cytotoxic T cell functions in X-linked lymphoproliferative disease. Blood, 103, 3821-7. eScholarID:1d10160

2003

• Arkwright PD, Pravica V, Geraghty P, Super M, Webb Ak, Schwarz M, Hutchinson I. (2003). End-organ dysfunction in cystic fibrosis: association with angiotensin I converting enzyme and cytokine gene polymorphisms. American Journal of Respiratory and Critical Care Medicine, 167( 3), 384-9. eScholarID:1d7031
• Rafatpanah H, Bennett E, Pravica VV, McCoy MJ, David TJ, Hutchinson IV, Arkwright PD. (2003). Association between novel GM-CSF gene polymorphisms and the frequency and severity of atopic dermatitis. Journal of Allergy and Clinical Immunology, 112(3):, 593-598. eScholarID:1d7454

2002

• Arkwright PD, Abinun M, Cant AJ. (2002). Autoimmunity in human primary immunodeficiency diseases. Blood, 99(8), 2694-2702. eScholarID:1d3973