Dr Chris Rose PhD, BEng
Role
I am a Research Fellow at the University of Manchester, UK. My research is at the intersection of medical imaging, statistical/machine learning, and medical image computing. I have a special interest in the development of methods for analyzing and exploiting heterogeneity in parametric maps of physiological measurements (e.g., blood flow). I have successfully applied these methods to evaluate drug efficacy and to predict how patients will respond to therapy. I am interested in a range of medical imaging modalities and disease areas, with most of my work focusing on cancer and magnetic resonance imaging (MRI).
Memberships of Committees and Professional Bodies
- Member of the International Society for Magnetic Resonance in Medicine.
Research
For details of my research, please see Chris Rose's personal web pages.
Qualifications
- PhD, The University of Manchester. Thesis title: "Statistical Models of Mammographic Texture and Appearance".
- BEng, Electronic Systems Engineering, The University of Manchester.
Collaborators and affiliated staff
- Prof Geoff Parker
- Prof Chris Taylor
- Dr James O'Connor
- Dr Penny Hubbard
- Prof John Waterton
- Dr Jo Naish
Selected publications
2011
- J P B O'Connor, C J Rose, A Jackson, Y Watson, S Cheung, F Maders, B J Whitcher, C Roberts, G A Buonaccorsi, G Thompson, A R Clamp, G C Jayson and G J M Parker. (2011). DCE-MRI biomarkers of tumour heterogeneity predict CRC liver metastasis shrinkage following bevacizumab and FOLFOX-6. British Journal of Cancer, 105, 139-145. eScholarID:125880 | DOI:doi:10.1038/bjc.2011.191
2010
- G. A. Buonaccorsi, C. J. Rose, J. P. B. O’Connor, C. Roberts, Y. Watson, A. Jackson, G. C. Jayson, G. J. M. Parker. (2010). Cross-visit Tumour Sub-segmentation and Registration with Outlier Rejection for Dynamic Contrast-Enhanced MRI Time Series Data. Presented at Medical Image Computing and Computer-Aided Intervention. Beijing, China. eScholarID:81576
2009
- James P.B. O'Connor, Richard A.D. Carano, Andrew R. Clamp, Jed Ross, Calvin C.K. Ho, Alan Jackson, Geoff J.M. Parker, Chris J. Rose, Franklin V. Peale, Michel Friesenhahn, Claire L. Mitchell, Yvonne Watson, Caleb Roberts, Lynn Hope, Sue Cheung, Hani Bou Reslan, Mary Ann T. Go, Glenn J. Pacheco, Xiumin Wu, Tim C. Cao, Sarajane Ross, Giovanni A. Buonaccorsi, Karen Davies, Jurjees Hasan, Paula Thornton, Olivia del Puerto, Napoleone Ferrara, Nicholas van Bruggen and Gordon C. Jayson. (2009). Quantifying Antivascular Effects of Monoclonal Antibodies to Vascular Endothelial Growth Factor. Clinical Cancer Research, 15(21), 6674-6682. eScholarID:81012 | DOI:10.1158/1078-0432.CCR-09-0731
- Mills S, Soh CC, O'Connor JP B, Rose CJ, Buonaccorsi G, Cheung SW, Zhao S, Parker GJM, Jackson A-. (2009). Tumour Enhancing Fraction (EnF) in Glioma: Relationship to Tumour Grade. European Radiology, 19(6), 1489-1498. eScholarID:1d28358 | DOI:10.1007/s00330-008-1288-z
- S. J. Mills, C. Soh, J. P. O’Connor, C. J. Rose, G. A. Buonaccorsi, S. Cheung, S. Zhao, G. J. Parker, and A. Jackson. (2009). Enhancing Fraction in Glioma and its relationship to the tumoural vascular microenvironment: A Dynamic Contrast Enhanced Magnetic Resonance Imaging Study. American Journal of Neuroradiology, 31, 726-731. eScholarID:81014 | DOI:10.3174/ajnr.A1925
- S.J. Mills, C. Soh, C.J. Rose, S. Cheung, S. Zhao, G.J.M. Parker and A. Jackson. (2009). Candidate Biomarkers of Extravascular Extracellular Space: A Direct Comparison of Apparent Diffusion Coefficient and Dynamic Contrast-Enhanced MR Imaging—Derived Measurement of the Volume of the Extravascular Extracellular Space in Glioblastoma Multiforme. American Journal of Neuroradiology, 31, 549-553. eScholarID:81011 | DOI:10.3174/ajnr.A1844