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School of Medicine

Professor  Kathryn Abel  MA MBBS FRCP FRCPsych PhD

Professor of Psychiatry

Centre for Women's Mental Health
3rd Floor Jean McFarlane Building
University of Manchester
Manchester M13 9PL

 

Research

Kathryn Abel is Professor of Psychiatry & Honorary Consultant Psychiatrist at the University of Manchester and Honorary Senior Lecturer at the Institute of Psychiatry, London. She is lead researcher for the Centre for Women's Mental Health Research Manchester.  She has a particular interest in women with schizophrenia and the outcomes of their offspring; the effects of sex on risk for neurodevelopmetnal disorder; the effect of prenatal exposures on fetal, childhood and adult mental health outcomes. She was an author of Into the Mainstream:a policy document for the Department of Health addressing the mental health needs of women. She has developed a practical guide to the implementation of women only day services for LITs and PCTs.

Kathryn is a member of the Primary Care Mental Health Research Group. Her interests include:

  • The mortality and morbidity of offspring exposed to parental mental illness in a population database usisng the Danish Research Registers.
  • Reassessing birth weight in schizophrenia; a longitudinal examination of the effects of sex, seasonality, migration and urbanicity in the Danish population.
  • Risk of obstetric, neurodevelopmental, forensic and adult psychiatric outcomes in the offspring of women explosed to periconceptional death of a first degree relative using the Danish population databases
  • The effect of maternal age at first birth on maternal and offspring outcomes using the Danish National Databases.
  • Women who kill: homicidal and infanticidal women and their pathways to care 
  • Women in prisons
  • RESPOND (Randomised Evaluation of antidepressants and Support for women with POstNatal Depression); A comparison of antidepressant and psychological therapy for PND in the community.
 

Collaborators and affiliated staff

Karolinska Institutet, Stockholm, Sweden

Universities of Oslo and Bergen, Norway

University of Bristol, UK

Columbai University, New York, USA

University of Western Australia, Perth, Australia

University of New South Wales, Sydney, Australia

 

Publications

2011

  • Flynn S, Abel KM, While D, Mehta H, Shaw J. (2011). Mental illness, gender and homicide: a population-based descriptive study. Psychiatry Research, 185, 368-375. eScholarID:86956 | DOI:10.1016/j.psychres.2010.07.040
  • Svensson A, Abel KM, Dalman C, Magnusson C. (2011). Implications of Advancing Paternal Age: Does it Affect Offspring School Performance? PLoS ONE, 6(9), 247-271. eScholarID:152187
  • Webb RT, Chris, Abel KM. (2011). Teenage motherhood and risk of premature death: long-term follow up in the ONS Longitudinal Study. Psychological Medicine, 41, 1867-1877-1877. eScholarID:152193
  • Abel KM, Susser ES, Brocklehurst P, Webb RT. (2011). Abortion and Mental Health. British Journal of Psychiatry, 199, BJP September 2011 199:180-186; doi:10.1192/bjp.bp.110.077230. eScholarID:152197

2010

  • Abel KM, Drake R, Goldstein J. (2010). Sex differences in schizophrenia: a review. International Review of Psychiatry, 22(5), 417-428. eScholarID:84725 | DOI:10.3109/09540261.2010.515205
  • Abel KM, Drake RJ, Goldstein J. (In-press). Sex differences in schizophrenia. International Review of Psychiatry, eScholarID:84728 | DOI:10.1016/j.psychres.2008.08.009
  • Abel KM, Rees S. (2010). The reproductive and sexual health of women service users: what's the fuss? Advances in Psychiatric Treatment, 16, 279-289. eScholarID:96650 | DOI:10.1192/apt.bp.108.006635
  • Abel KM, Wicks S, Susser E, Dalman C, Petersen M, Mortensen PB, Webb RT. (In-press). Birth weight, schizophrenia and adult mental disorder: is risk confined to the smallest babies? Archives of General Psychiatry, 67, 923-930. eScholarID:84726 | DOI:10.1001/archgenpsychiatry.2010.100
  • Laursen T, Munk Olsen T, Mortensen PB, Abel KM, Appleby L, Webb RT. (2010). Filicide in offspring of parents with severe psychiatric disorders. Journal of Clinical Psychiatry, 2010, eScholarID:96649
  • Sharp DJ, Chew-Graham C, Tylee A, Lewis G, Howard L, Anderson I, et al. (2010). A pragmatic randomised controlled trial to compare antidepressants with a community-based psychosocial intervention for the treatment of women with postnatal depression. Health Technology Assessment, 14, eScholarID:80614
  • Stone JM, Abel KM, Allen MPG, van Haren N, Matsumoto K, McGuire PK, Fu CHY. (2010). Ketamine-induced disruption of verbal self monitoring linked to superior temporal activation. Pharmacopsychiatry, (44), 41. eScholarID:120004
  • Webb RT, Wicks S, Dalman C, Pickles AR, Appleby L, Mortensen PB, Haglund B, Abel KM. (2010). Influence of environmental factors in higher risk of sudden infant death syndrome linked with parental mental illness. Archives of General Psychiatry, 67, 69-77. eScholarID:80617 | DOI:10.1001/archgenpsychiatry.2009.172

2009

  • Khashan AS, McNamee R, Abel KM, Mortensen PB, Kenny LC, Pederson MG, Webb RT, Baker PN. (2009). Rates of preterm birth following antenatal maternal expsure to severe life events: a population-based cohort study. Human Reproduction, 24(2), 429-437. eScholarID:96651 | DOI:10.1093/humrep/den418
  • Khashan AS, Mortensen PB, McNamee R, Baker PN, Abel KM. (2009). Sex ratio at birth following prenatal maternal exposure to severe life events: a population-based cohort study. Human Reproduction, 1(1), 1-4. eScholarID:80619
  • King-Hele S, Webb R, Mortensen PB, Appleby L, Pickles A, Abel KM. (2009). Risk of stillbirth and neonatal death linked with maternal mental illness: a national cohort study. Archives of Disease in Childhood Fetal and Neonatal Edition, 94, F105-F110. eScholarID:80618 | DOI:10.1136/adc.2007.135459
  • Short V, Cooper J, Shaw J, Kenning C, Abel KM, Chew-Graham C. (2009). Custody vs care: attitudes of prison staff to self-harm in women prisoners - a qualitative sstudy. Journal of Forensic Psychiatry and Psychology, 20(3), 408-426. eScholarID:80615 | DOI:10.1080/14789940802377114

2008

  • Abel K, Heathlie HF, Howard LM, Webb RT. (2008). Sex- and age-specific incidence of fractures in mental illness: a historical population-based cohort study. Journal of Clinical Psychiatry, 69, 1398-1404. eScholarID:1d17556
  • Khashan A, Abel K, McNamee R, Goertz M, Baker PN, Webb RT, Kenny L, Mortensen PB. (2008). Higher risk of offspring schizophrenia following prenatal exposure to severe life events. Archives Of General Psychiatry, 65(2), 146-152. eScholarID:1d28178 | DOI:10.1001/archgenpsychiatry.2007.20
  • Khashan A, McNamee R, Abel K, Pedersen MG, Webb RT, Kenny L, Mortensen PB, Baker PM. (2008). Reduced infant birthweight consequent upon maternal exposure to severe life events. Psychosomatic Medicine, 70, 688-694. eScholarID:1d17558 | DOI:10.1097/PSY.0b013e318177940d
  • Wan M, Moulton S, Abel K. (2008). The service needs of mothers with schizophrenia: A qualitative study of perinatal psychiatric and antenatal workers. General Hospital Psychiatry, 30, 177-184. eScholarID:1d16783 | DOI:10.1016/j.genhosppsych.2007.12.001
  • Wan M, Steff Moulton, Abel K. (2008). A review of mother-child relational interventions and their usefulness for mothers with schizophrenia. Archives of Women's Mental Health, 11(3), 171-179. eScholarID:1d17143 | DOI:10.1007/s00737-008-0010-0
  • Wan M, Warren K, Salmon MP, Kathryn M Abel. (2008). Patterns of maternal responding in postpartum mothers with schizophrenia. Infant Behavior and Development, 31, 532-538. eScholarID:1d17145 | DOI:10.1016/j.infbeh.2008.04.003
  • Wan MW, Abel KM, Green J. (2008). The transmission of risk to children from mothers with schizophrenia. A developmental psychopathology model. Clinical Psychology Review, 28, 613-637. eScholarID:68355 | DOI:10.1016/j.cpr.2007.09.001
  • Wan MW, Penketh V, Salmon M, Abel KM. (2008). The content and style of speech from mothers with schizophrenia towards their infants. Psychiatry Research, 159(1-2), 109-114. eScholarID:68346 | DOI:10.1016/j.psychres.2007.05.012
  • Webb RT, Pickles AR, King-Hele SA, Appleby L, Mortensen PB, Abel KM. (2008). Parental mental illness and fatal birth defects in a national birth cohort. Psychological Medicine, 38, 1495-1503. eScholarID:68262
  • Abel KM, Morgan V, Webb RT. (2008). Taking the spotlight off schzophrenia. British Journal of Psychiatry, 193, 311-315. eScholarID:68317
  • Webb R, Appleby L, Pickles A, King-Hele S, Mortensen PB, Abel K. (2008). High offspring mortality risks with maternal and paternal schizophrenia and other sever mental disorders: elevated risks persist beyond the neonatal period. Canadian Journal of Psychiatry, 53, 868. eScholarID:68377

2007

  • Abel K, Allin MA, van Amelsvoort T, Hemsley D, Geyer MA. (2007). The indirect serotonergic agonist d-fenfluramine and prepulse inhibition in healthy men. Neuropharmacology, 52, 1088-1094. eScholarID:1d17561
  • Flynn SM, Shaw J, Abel K. (2007). Homicide of infants: a cross-sectional study. Journal of Clinical Psychiatry, 68, 1501-1509. eScholarID:1d17560
  • King-Hele S, Abel K, Webb RT, Mortensen P, Appleby L, Pickles A. (2007). Risk of sudden infant death syndrome with parental mental illness. Archives of General Psychiatry, 64(11), 1323-1330. eScholarID:1d16581
  • Wan MW, Salmon MP,, Riordan DM, Appleby L, Abel KM. (2007). What predicts poor mother-infant interaction in schizophrenia? Psychological Medicine, 37, 537-546. eScholarID:68264
  • Webb R, Pickles A, Appleby L, Mortensen PB, Abel KM. (2007). Death by unnatural causes during childhood and early adulthood in offspring of psychiatric inpatients. Archives of General Psychiatry, 64, 345-352. eScholarID:68265

2006

  • Abel K, Kulkarni JJ. (2006). Women & Depression. Women and Mood Disorder. Cambridge University Press. eScholarID:3d911
  • Abel K, Warburton AL. (2006). Domestic violence and its impact on mood disorder in women: implications for mental heatlh workers. Mood and Anxiety Disorders in Women. Cambridge University Press. eScholarID:3d257
  • Abel K, Warburton AL. (2006). Women & Violence. Women and Mood Disorder. Cambridge University Press. eScholarID:3d910
  • Abel K. (2006). Perinatal & Gynaecological Liaison. Principles of Liaison Psychiatry. Cambridge University Press. eScholarID:3d535
  • Wan MW, Warburton AL, Appleby L, Abel KM. (2006). Mother and Baby Unit admissions: a feasibility study examining child outcomes four to six years on. Australian and New Zealand Journal of Psychiatry, 41, 150-156. eScholarID:68266
  • Webb RT, Abel K, Pickles A, Appleby L, King-Hele S, Mortensen PB. (2006). Mortality risk among offspring of psychiatric inpatients: a population-based follow-up to early adulthood. American Journal of Psychiatry, 163 (12), 2170-2177. eScholarID:1d14395 | DOI:10.1176/appi.ajp.163.12.2170
  • Abel KJ, Allin MA, Jirtle RL. (2006). Letter in response to Goldacre MJ, et al Schizophrenia and cancer: an epidemiological study. British Journal of Psychiatry, 187, 334-338. eScholarID:68322

2005

  • Allin MA, Abel K. (2005). Placental Programming & Neurodevelopmental Outcomes. Placenta and Neurodisability. eScholarID:3d293
  • Abel K, Webb RT, Salmon M, Wan M, Appleby L. (2005). Prevalence and predictors of parenting outcomes in a cohort of mothers with schizophrenia admitted for joint mother and baby psychiatric care in England. Journal of Clinical Psychiatry, 66(6), 781-789. eScholarID:1d12259
  • Fu C, Abel K, Allin M, Gasston D, Costafreda S, Suckling J, Williams S, McGuire P. (2005). Effects of ketamine on prefrontal and striatal regions in an overt verbal fluency task: a functional magnetic resonance imaging study. Psychopharmacology, 183(1), 1045-1056. eScholarID:1d12321 | DOI:10.1007/s00213-005-0154-9
  • Webb R, Abel KM, Pickles A, Appleby L. (2005). Mortality in the offspring of people with psychotic disorders: a critical review and meta-analysis. American Journal of Psychiatry, 162, 1045-1056. eScholarID:68357

2004

  • Abel K. (2004). Treating psychological disorders during pregnancy and lactation. Textbook of Gender Specific Medicine. Elsevier Science. eScholarID:3d294
  • Guthrie, Creed, Abel K. (2004). Perinatal & Gynaecological Liaison. Principles of Liaison Psychiatry. Cambridge University Press. eScholarID:3d734
  • Abel K, Jolley S, Hemsley D, Geyer M. (2004). The influence of schizotypy traits on prepulse inhibition in young healthy controls. J Psychopharmacol, 18( 2), 181-8. eScholarID:1d28703
  • Abel K. (2004). Foetal origins of schizophrenia: testable hypotheses of genetic and environmental influences. Br J Psychiatry, 184, 383-5. eScholarID:1d9310
  • Howard L, Webb RT, Abel K. (2004). Safety of antipsychotic drugs for pregnant and breastfeeding women with non-affective psychosis. BMJ, 329( 7472), 933-4. eScholarID:1d9311
  • Ranote S, Elliott R, Abel K, Mitchell R, Deakin JFW, Appleby L. (2004). The neural basis of maternal responsiveness to infants: an fMRI study. Neuroreport, 15( 11), 1825-9. eScholarID:1d9309
  • Salmon MP, Abel K, Webb RT, Warburton AL, Appleby L. (2004). A national audit of joint mother and baby admissions to UK psychiatric hospitals: an overview of findings. Archives of Women's Mental Health, 7( 1), 65-70. eScholarID:1d7796 | DOI:10.1007/s00737-003-0042-4
  • Webb RT, Howard L, Abel K. Antipsychotic drugs for non-affective psychosis during pregnancy and postpartum., Cochrane Database of Systematic Reviews. Vol. ( 2). 2004. 1469-493X. CD004411. eScholarID:19d107

2003

  • Legato M, Abel K. (2003). Treating psychological disorders during pregnancy and lactation. Textbook of Gender specific Medicine. Elsevier Science. eScholarID:3d220
  • Abel K, Allin M, Hemsley D, Geyer M. (2003). Low dose ketamine increases prepulse inhibition in healthy men. Neuropharmacology, 44( 6), 729-37. eScholarID:1d12322 | DOI:10.1016/S0028-3908(03)00073-X
  • Abel K, Allin M, Kucharska-Pietura K, David A, Andrew C, Williams S, Brammer M, Phillips M. (2003). Ketamine alters neural processing of facial emotion recognition in healthy men: an fMRI study. Neuroreport, 14( 3), 387-91. eScholarID:1d30247
  • Abel K, Allin MPG, Hemsley DR, Geyer MA. (2003). Low dose ketamine increases prepulse inhibition in healthy men. Neuropharmacology, 44, 729-737. eScholarID:1d25202
  • Abel K, Allin MPG, Kucharska-Pietura K, Andrew C, Williams S, David AS, Philips ML. (2003). Ketamine and fMRI BOLD signal: Distinguishing between effects mediated by change in blood flow versus change in cognitive state. Human Brain Mapping, 18(2), 135-145. eScholarID:1d25201
  • Abel K, Allin MPG, Kucharska-Pietura K, David A, Andrew C, Williams S, Brammer MJ, Philips ML. (2003). Ketamine alters neural processing of facial emotion recognition in healthy men: An fMRI study. NeuroReport, 14(3), 387-391. eScholarID:1d25203
  • Salmon M, Abel K, Cordingly L, Friedman T, Appleby L. (2003). Clinical and parenting skills outcomes following joint mother-baby psychiatric admission. Aust & NZ J Psychiatry, eScholarID:1d25204
  • Salmon MP, Abel K, Cordingley ME, Friedman T, Appleby L. (2003). Clinical and parenting skills outcomes following joint mother-baby psychiatric admission. Aust N Z J Psychiatry, 37( 5), 556-62. eScholarID:1d9339

2002

  • Abel K, Castle D J. (2002). Can estrogens account for sex differences in schizophrenia?. Psychiatric Illness in Women: Emerging treatments and Research. ( Chapter 13, pp. 331-347). eScholarID:3d374
  • Abel K, Castle DJ. (2002). Can estrogens account for sex differences in schizophrenia. Psychiatric Illness in Women: Emerging treatments and Research. American Psychological Association. eScholarID:3d536
  • Abel K. (2002). Psychiatric illness and its management in pregnancy and the puerperium. Contemporary Clinical Gynecology and Obstetrics. ( 2, ). eScholarID:3d905
  • Abel K. (2002). Psychiatric illness and its management in pregnancy and the puerperium. Contemporary Clinical Gynecology and Obstetrics. ( Vol 2 (1), pp. 59-71). eScholarID:3d993
  • van Amelsvoort T, Murphy D, Robertson, Daly E, Whitehead M, Abel K. (2002). Effect of Long-term estrogen replacement therapy on growth hormone response to pyridostigmine in healthy postmenopausal women. Psychoneuroendocrinology, 28(1), 101-112. eScholarID:1d25200

2001

  • Craig M, Abel K. (2001). Psychoactive drug prescribing during pregnancy and lactation. Baillière's Best Practise and Research: Clinical Obstetrics and Gynaecology. ( 15, ). eScholarID:3d832
  • Craig M, Abel K. (2001). Psychoactive drug prescribing during pregnancy and lactation. Bailliere's Best Practice and Research: Clinical Obstetrics and Gynaecology, 15 (6), 1013-1030. eScholarID:1d23978
  • van Amelsvoort T.M.J, Abel K, Robertson D M, Daly E, Critchley H, Whitehead M, Murphy D G M. (2001). Prolactin response to d-fenfluramine in postmenopausal women on and off ERT: comparison with young women. Psychoneuroendocrinology, 6, 493-502. eScholarID:1d23977

2000

  • Abel K. (2000). Psychopharmacology. Core Postgraduate Psychiatry. eScholarID:3d711

1999

  • Abel K, Cleare A J. (1999). Peripheral Hormonal responses to D fenfluramine as a probe of central serotonergic function in humans. Psychopharmacology, 142/1, 68-72. eScholarID:1d23979

1998

  • Abel K, Waikar M, Pedro B, Hemsley D, Geyer M. (1998). Repeated testing of PPI and habituation of the startle reflex: a study in healthy human controls. journal of Psychopharmacology, 12, eScholarID:1d17562

1997

  • Abel K. (1997). The Biology of Schizophrenia. Understanding the Biology of Mental Illness. eScholarID:3d906
  • Abel K, O'Keane V, Murray RM, Cleare AJ. (1997). Serotonergic function and negative and depressive symptomatology in schizophrenia and major depression. Psychoneuroendocrinology, 22, eScholarID:1d17563

1996

  • Abel K, Pound A. (1996). Motherhood and Mental Illness. Planning Community Mental Health Services for Women: A multiprofessional handbook. Routledge. eScholarID:3d833
  • Abel K, O'Keane V, Murray RM. (1996). Enhancement of the Prolactin response to D-fenfluramine challenge in drug-naive schizophrenia. British Journal of Psychiatry, 168, eScholarID:1d17564
  • Abel K, O'Keane V, Sherwood R, Murray RM. (1996). Plasma Homovanillic acid profiles at different phases of the Ovulatory cycle in Healthy women. Biological Psychiatry 39, 12, eScholarID:1d17565
  • Cleare AJ, O'Keane V, Abel K. (1996). Pharmacological evidence that depressive symptoms do not share a common serotonergic mechanism across diagnoses. European Psychiatry, 11, eScholarID:1d33157
  • Dassa D, Sham PC, van Os J, Abel K. (1996). Season of birth, obstetric complications and schizophrenia. Encephale, 22, eScholarID:1d33081
  • Trudie Hilton, David Taylor, Abel K. (1996). Which dose of Haloperidol? Psychiatric Bulletin 359, 6, eScholarID:1d33288
  • Dassa D, Sham PC, van Os J, Abel K. Relationship of birth season to clinical features, family history, and obstetric complications in schizophrenia, Psychiatry Research. Vol. 64. 1996. eScholarID:19d163

1995

  • Castle DJ, Abel K, Takei N, Murray RM. (1995). Gender differences in schizophrenia: Hormonal effect or subtypes?. Schizophrenia Bulletin, 21, eScholarID:1d33082

1994

  • O'Keane V, Abel K, Murray RM. (1994). Growth hormone responses to Pyridostigmine in schizophrenia: Evidence for cholinergic dysfunction. Psychiatry, 36, eScholarID:1d32894

1991

  • Abel K, Stewart K, Rai GS. (1991). An audit of rectal examination on general/geriatric wards in a district general hospital. British Journal of Clinical Practice, 45, eScholarID:1d17566

1990

  • Stewart K, Abel K, Rai GS. (1990). Resuscitation decisions in a general hospital. British Medical Journal, eScholarID:1d33289

  • (In-press). Attitudes and adjustment to the parental role in mothers following treatment for postnatal depression. Journal of Affective Disorders, eScholarID:84724
  • Wan MW, Howard L, Sharp D, Abel KM. (In-press). Attitudes and adjustment to the parental role in mothers following treatment for postnatal depression. Journal of Affective Disorders, eScholarID:120002
  • Webb RT, Abel KM. (In-press). Teenage motherhood and risk of premature death: long-term follow up in the ONS Longitudinal study. eScholarID:119963
  • Webb RT, Chris, Abel KM. (In-press). Teenage motherhood and risk of premature death: long-term follow up in the ONS Longitudinal Study. Psychological Medicine, eScholarID:133183

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